超声乳化术后角膜Q值与泪膜参数的改变

山东大学学报(医学版) ›› 2011, Vol. 49 ›› Issue (3): 102-105.

超声乳化术后角膜Q值与泪膜参数的改变

高云霞1，吴欣怡1，刘方毅2，王强2，郑开申2

1.山东大学齐鲁医院眼科，济南 250012; 2.临沂市人民医院眼科, 山东临沂 276003

收稿日期:2010-11-29 出版日期:2011-03-10 发布日期:2011-03-10
通讯作者: 吴欣怡(1956- ),女，教授，博士生导师，主要从事角膜病与白内障的研究。
作者简介:高云霞（1977- ），女，主治医师，博士研究生，主要从事角膜病与白内障的研究。

Changes of corneal Q values and lacrimal film parameters after phacoemulsification

GAO Yun-xia1, WU Xin-yi1, LIU Fang-yi2, WANG Qiang2, ZHENG Kai-shen2

1. Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan 250012, China;
2. Department of Ophthalmology, Linyi People′s Hospital, Linyi 276003, Shandong, China

Received:2010-11-29 Online:2011-03-10 Published:2011-03-10

摘要/Abstract

摘要：

目的研究白内障超声乳化术后角膜非球面状态与泪膜参数的改变。方法选取临沂市人民医院白内障患者102例146眼分成透明角膜切口组（A组，48例71眼），巩膜切口组（B组，54例75眼）。分别于白内障超声乳化术前，术后1d、1周、1个月、3个月进行角膜地形图、角膜荧光素染色试验和泪膜破裂时间（BUT）检查，并记录角膜Q 值、BUT值、荧光素试验分值与干眼症状眼数。结果 ①泪膜破裂时间术后1d、1周、1月与术前比较有明显缩短(P<0.05)；角膜荧光素试验与干眼症状术后1周内变化明显，术后3月基本恢复正常；②所有患者角膜Q值手术后1d、1周、1个月与术前比较差异有统计学意义（P<0.05）；术后1d A组与B组间对应观察点比较，角膜Q值差异有统计学意义。③术后1d角膜Q值改变（0.132+0.139）与泪膜破裂时间变化（6.500+2.111s）行Pearson相关分析，R=0.215, P=0.001。结论白内障超声乳化术后角膜非球面形态与泪膜参数早期都会有不同程度的改变，随着切口的愈合渐趋恢复；早期角膜Q值改变与泪膜破裂时间改变存在相关性。

关键词: 超声乳化术；角膜；泪膜；Q值

Abstract:

Objective To investigate changes of corneal aspherical parameters and lacrimal film parameters after cataract phacoemulsification. Methods 102 patients (146 eyes) from the Linyi People′s Hospital that underwent ultrasonic phacoemulsification were divided into the corneal incision group ( group A, 48 cases with 71 eyes ) and the scleral incision group( group B, 54 cases with 75 eyes). The symptoms of dry eye, tear breakup time(BUT), corneal fluorescein staining and corneal map were measured preoperatively and 1 day, 1week, 1month and 3months postoperatively. Results ①BUT values 1 day,1 week and 1 month postoperatively were shorter than preoperative(P<0.05), corneal fluorescein and dry eye symptom changed significantly 1 week postoperatively, and returned to normal after 3 months. ②The corneal Q value apparently changed 1day, 1week and 1month postoperatively (P<0.05) and there was no statistical significance between groups A and B, except 1 day postoperatively. ③Pearson correlation analysis revealed a statistically significant correlation between changes of the Q value (0.132+0.139) and BUT(6.500+2.111s) 1 day postoperatively(R=0.215, P=0.001). Conclusions In the early stage after phacoemulsification, corneal aspherical and lacrimal film parameters have some changes, and there is a correlation between them. Then all the parameters return to normal with the healing of incisions.

Key words: Phacoemulsification; Cornea; Lacrimal film; Q-value

中图分类号:

R775

高云霞1，吴欣怡1，刘方毅2，王强2，郑开申2. 超声乳化术后角膜Q值与泪膜参数的改变[J]. 山东大学学报(医学版), 2011, 49(3): 102-105.

GAO Yun-xia1, WU Xin-yi1, LIU Fang-yi2, WANG Qiang2, ZHENG Kai-shen2 . Changes of corneal Q values and lacrimal film parameters after phacoemulsification[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2011, 49(3): 102-105.

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