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山东大学学报 (医学版) ›› 2020, Vol. 58 ›› Issue (3): 58-61.doi: 10.6040/j.issn.1671-7554.0.2020.214

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重症新型冠状病毒肺炎1例并文献复习

温鹏1,董亮2,王欣3,魏敏1,刘岩1,徐玉荣1,孙文青1,周明香1   

  1. 1.山东大学附属山东省胸科医院呼吸与危重症医学科, 山东 济南 250013; 2.山东大学齐鲁医院呼吸与危重症医学科, 山东 济南 250012; 3.山东第一医科大学附属中心医院呼吸与危重症医学科, 山东 济南 250013
  • 出版日期:2020-03-10 发布日期:2022-09-27
  • 通讯作者: 董亮. E-mail:dl5506@126.com

Severe novel coronavirus pneumonia: a case report and literature review

WEN Peng1, DONG Liang2, WANG Xin3, WEI Min1, LIU Yan1, XU Yurong1, SUN Wenqing1, ZHOU Mingxiang1   

  1. 1. Department of Respiratory Medicine, Shandong Provincial Chest Hospital Affiliated to Shandong University, Jinan 250013, Shandong, China;
    2. Department of Respiratory Medicine, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China;
    3. Department of Respiratory Medicine, Jinan Central Hospital Affiliated to Shandong First Medical University, Jinan 250013, Shandong, China
  • Online:2020-03-10 Published:2022-09-27

摘要: 目的 描述1例重症新型冠状病毒肺炎患者的诊治过程,帮助临床医生更好地认识和管理新型冠状病毒肺炎。 方法 回顾性分析1例重症新型冠状病毒肺炎患者的发病、发展、治疗及结局,并复习相关文献。 结果 患者病初表现为发热、干咳,后病情进展,出现呼吸困难,胸部CT示双肺渗出影。根据专家组意见,患者接受洛匹那韦/利托那韦、干扰素α-2b和人血丙种球蛋白等治疗,2周后病愈出院。 结论 恰当的管理策略可以达到对新型冠状病毒肺炎有效诊疗的目的。

关键词: 2019新型冠状病毒, 重症肺炎, 干扰素α-2b, 洛匹那韦/利托那韦, 人血丙种球蛋白

Abstract: Objective To describe the diagnosis and treatment of a patient with severe novel coronavirus pneumonia, and to improve the understanding and management of clinicians on novel coronavirus pneumonia. Methods The onset, development, treatment and outcome of a patient with severe 2019 novel coronavirus pneumonia were retrospectively analyzed and relevant literatures were reviewed. Results At the beginning of the disease, the patient presented fever and dry cough, and later the disease progressed to dyspnea. Chest CT showed bilateral exudation of the lung. Lopinavir/ritonavir, IFN-α and immunoglobulin were given to the patient according to the expert groups opinion. The pneumonia was cured and the patient was discharged two weeks later. Conclusion Appropriate management strategies are effective on diagnosis and treatment of new coronavirus pneumonia.

Key words: 2019 novel coronavirus, Severe pneumonia, Interferon α-2b, Lopinavir/ritonavir, Immunoglobulin

中图分类号: 

  • R563.1
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[2] 许天一,吴萍,王爱玲,陈丽萍. 米力农雾化治疗小儿重症肺炎合并心力衰竭的疗效[J]. 山东大学学报(医学版), 2016, 54(7): 88-90.
[3] 刘志荣,王磊,吕卉,于淑丽. 干扰素和利巴韦林联合用药对慢性丙型肝炎患者肝组织中α-SMA、TIMP-1的影响[J]. 山东大学学报(医学版), 2007, 45(4): 365-368.
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