您的位置:山东大学 -> 科技期刊社 -> 《山东大学学报(医学版)》

山东大学学报 (医学版) ›› 2018, Vol. 56 ›› Issue (3): 24-28.doi: 10.6040/j.issn.1671-7554.0.2017.1198

• • 上一篇    

外周神经电刺激治疗膀胱过度活动症进展

张鹏   

  1. 首都医科大学附属北京朝阳医院泌尿外科, 北京 100020
  • 收稿日期:2017-12-04 发布日期:2022-09-27
  • 通讯作者: 张鹏. E-mail:zhang130917@163.com
  • 基金资助:
    北京市卫生系统高层次卫生技术人才培养项目(2015-3-030)

Advances of peripheral nerve stimulation in the treatment of overactive bladder

ZHANG Peng   

  1. Department of Urology, Beijing Chao-yang Hospital, Capital Medical University, Beijing 100020, China)
  • Received:2017-12-04 Published:2022-09-27

摘要: 膀胱过度活动症(OAB)是一种常见的下尿路疾病,是以尿急症状为主的症候群,伴或不伴急迫性尿失禁,常伴有尿频与夜尿症状。作为III线治疗方案之一——外周神经电刺激可用于保守治疗方法失败的患者。对外周神经电刺激的发展历史、作用机制、临床效果及相关基础研究做一综述。

关键词: 膀胱过度活动症, 胫神经电刺激, 骶神经电刺激, 阴部神经电刺激

Abstract: Overactive bladder(OAB)is a symptom complex, which includes urinary urgency, frequency, and nocturia with or without incontinence. Peripheral nerve stimulation is one of the effective ways to cure patients who have failed to respond to conservative treatments as the third line therapy. This paper reviews the history, mechanism, clinical efficacy and related researches of peripheral nerve stimulation in the treatment of OAB.

Key words: Overactive bladder, Tibial nerve stimulation, Sacral nerve stimulation, Pudendal nerve stimulation

中图分类号: 

  • R694
[1] Abrams P. Describing bladder storage function: overactive bladder syndrome and detrusor overactivity[J]. Urology, 2003, 62(5 Suppl 2): 28-37.
[2] Abrams P, Cardozo L, Fall M, et al. The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society[J]. Urology, 2003, 61(1): 37-49.
[3] Haylen BT, de Ridder D, Freeman RM, et al. An International Urogynecological Association(IUGA)/International Continence Society(ICS)joint report on the terminology for female pelvic floor dysfunction[J]. Neurourol Urodyn, 2010, 29(1): 4-20.
[4] Osman NI, Chapple CR. Overactive bladder syndrome: current pathophysiological concepts and therapeutic approaches[J]. Arab J Urol, 2013, 11(4): 313-318.
[5] Lee JG, Wein AJ, Levin RM. The effect of caffeine on the contractile response of the rabbit urinary bladder to field stimulation[J]. Gen Pharmacol, 1993, 24(4): 1007-1011.
[6] Ouslander JG. Management of overactive bladder[J]. N Engl J Med, 2004, 350(8): 786-799.
[7] Burgio KL. Influence of behavior modification on overactive bladder[J]. Urology, 2002, 60(5 Suppl 1): 72-76.
[8] de Groat WC, Griffiths D, Yoshimura N. Neural control of the lower urinary tract[J]. Compr Physiol, 2015, 5(1): 327-396.
[9] Smith AL, Wein AJ. Recent advances in the development of antimuscarinic agents for overactive bladder[J]. Trends Pharmacol Sci, 2010, 31(10): 470-475.
[10] Wallace KM, Drake MJ. Overactive bladder[J]. F1000 Res, 2015, 7: 4. pii: F1000 Faculty Rev-1406. doi: 10.12688/f1000research.7131.1. eCollection 2015.
[11] Gormley EA, Lightner DJ, Faraday M, et al. Diagnosis and treatment of overactive bladder(non-neurogenic)in adults: AUA/SUFU guideline amendment[J]. J Urol, 2015, 193(5): 1572-1580.
[12] Schmidt RA, Jonas U, Oleson KA, et al. Sacral nerve stimulation for treatment of refractory urinary urge incontinence. Sacral Nerve Stimulation Study Group[J]. J Urol, 1999, 162(2): 352-357.
[13] van Kerrebroeck PE, van Voskuilen AC, Heesakkers JP, et al. Results of sacral neuromodulation therapy for urinary voiding dysfunction: outcomes of a prospective, worldwide clinical study[J]. J Urol, 2007, 178(5): 2029-2034.
[14] White N, Iglesia CB. Overactive bladder[J]. Obstet Gynecol Clin North Am, 2016, 43(1): 59-68.
[15] 廖利民. 神经源性膀胱的治疗现状和进展[J]. 中国康复医学杂志, 2011, 26(3): 201-205.
[16] Pettit PD, Thompson JR, Chen AH. Sacral neuromodulation: new applications in the treatment of female pelvic floor dysfunction[J]. Curr Opin Obstet Gynecol, 2002, 14(5): 521-525.
[17] Craggs M, McFarlane J. Neuromodulation of the lower urinary tract[J]. Exp Physiol, 1999, 84(1): 149-160.
[18] Katona F, Berenji M. Intravesieal transurethral electrotherapy in meningomyelocele patients[J]. Acta Paediatr Acad Sci Hung, 1975, 16(3-4): 363-374.
[19] Tanagho EA, Schmidt RA, Orvis BR. Neural stimulation for control of voiding dysfunction: a preliminary report in 22 patients with serious neuropathic voiding disorders[J]. J Urol, 1989, 142(2 Pt 1): 340-345.
[20] McGuire EJ, Zhang SC, Horwinski ER, et al. Treatment of motor and sensory detrusor instability by electrical stimulation[J]. J Urol, 1983, 129(1): 78-79.
[21] Peters KM, Feber KM, Bennett RC. Sacral versus pudendal nerve stimulation for voiding dysfunction: a prospective, single-blinded, randomized, crossover trial[J]. Neurourol Urodyn, 2005, 24(7): 643-647.
[22] Shaker HS, Hassouna M. SacraI root neuromodulation: an effective treatment for refractory urge incontinence[J]. J Urol, 1998, 159(5): 1516-1519.
[23] Fall M, Carlsson C, Erlandson BE. Electrical stimulation in interstitial cystitis[J]. J Urol, 1980, 123(2): 192-195.
[24] de Groat WC, Yoshimura N. Mechanisms underlying the recovery of lower urinary tract function following spinal cord injury[J]. Prog Brain Res, 2006, 152: 59-84.
[25] Griffiths D. Neural control of micturition in humans: a working model[J]. Nat Rev Urol, 2015, 12(12): 695-705.
[26] Andersson KE, Arner A. Urinary bladder contraction and relaxation: physiology and pathophysiology[J]. Physiol Rev, 2004, 84(3): 935-986.
[27] de Groat WC. Spinal cord projections and neuropeptides in visceral afferent neurons[J]. Prog Brain Res, 1986, 67: 165-187.
[28] Janig W, Morrison JF. Functional properties of spinal visceral afferents supplying abdominal and pelvic organs, with special emphasis on visceral nociception[J]. Prog Brain Res, 1986, 67: 87-114.
[29] Bartley J, Gilleran J, Peters K. Neuromodulation for overactive bladder[J]. Nat Rev Urol, 2013, 10(9): 513-521.
[30] Zhang F, Zhao S, Shen B, et al. Neural pathways involved in sacral neuromodulation of reflex bladder activity in cats[J]. Am J Physiol Renal Physiol, 2013, 304(6): 710-717.
[31] de Groat WC, Ryall RW. Reflexes to sacral parasympathetic neurones concerned with micturition in the cat[J]. J Physiol, 1969, 200(1): 87-108.
[32] Rogers MJ, Xiao Z, Shen B, et al. Propranolol, but not naloxone, enhances spinal reflex bladder activity and reduces pudendal inhibition in cats[J]. Am J Physiol Regul Integr Comp Physiol, 2015, 308(1): 42-49.
[33] Tai C, Chen M, Shen B, et al. Plasticity of urinary bladder reflexes evoked by stimulation of pudendal afferent nerves after chronic spinal cord injury in cats[J]. Exp Neurol, 2011, 228(1): 109-117.
[34] Caremel R, Nouhaud FX, Leroi AM, et al. Results of sacral neuromodulation on the urinary and fecal incontinence and sexuality in 20 women suffering from double incontinence[J]. Prog Urol, 2012, 22(7): 424-432.
[35] Govaert B, Maeda Y, Alberga J, et al. Medium. term outcome of sacral nerve modulation for constipation[J]. Dis Colon Rectum, 2012, 55(1): 26-31.
[36] Sukhu T, Kennelly MJ, Kurpad R. Sacral neuromodulation in overactive bladder: a review and current perspectives[J]. Res Rep Urol, 2016, 8: 193-199. eCollection 2016.
[37] Leong RK, De Wachter SG, Nieman FH, et al. PNE versus 1st stage tined lead procedure: a direct comparison to select the most sensitive test method to identify Patients suitable for sacral neuromodulation therapy[J]. Neurourol Urodyn, 2011, 30(7): 1249-1252.
[38] 陈国庆, 廖利民. 骶神经调节术治疗下尿路功能障碍: 单中心14年经验总结[J]. 微创泌尿外科杂志, 2016,5(5): 263-267. CHEN Guoqing, LIAO Limin. Sacral neuromodulation for lower urinary tract dysfunction: 14-year experience at single center[J]. Journal of Minimally Invasive Urology, 2016, 5(5): 263-267.
[39] Marcelissen TA, Leong RK, Nieman FH, et al.The effect of pulse rate changes on the clinical outcome of sacral neuromodulation[J]. J Urol, 2011, 185(5): 1781-1785.
[40] Ismail S, Chartier-Kastler E, Perrouin-Verbe MA, et al. Long-term functional outcomes of S3 sacral neuromodulation for the treatment of idiopathic overactive bladder[J]. Neuromodulation, 2017, 20(8): 825-829.
[41] Noblett K, Siegel S, Mangel J, et al. Results of a prospective, multicenter study evaluating quality of life, safety, and efficacy of sacral neuromodulation at twelve months in subjects with symptoms of overactive bladder[J]. Neurourol Urodyn, 2016, 35(2): 246-251.
[42] Marcelissen TA, Leong RK, de Bie RA, et al. Long-term results of sacral neuromodulation with the tined lead procedure[J]. J Urol, 2010, 184(5): 1997-2000.
[43] Tai C, Smerin SE, de Groat WC, et al. Pudendal-to-bladder reflex in chronic spinal-cord-injured cats[J]. Exp Neurol, 2006, 197(1): 225-234.
[44] Bansal U, Fuller TW, Jiang X, et al. Lumbosacral spinal segmental contributions to tibial and pudendal neuromodulation of bladder overactivity in cats[J]. Neurourol Urodyn, 2017, 36(6): 1496-1502.
[45] Li T, Feng X, Lv J, et al. Short-term clinical efficacy of electric pudendal nerve stimulation on neurogenic lower urinary tract disease: a pilot research[J]. Urology, 2017. pii: S0090-4295(17)31210-4. doi: 10.1016/j.urology.2017.10.047.[Epub ahead of print].
[46] Li ALK, Marques R, Oliveira A, et al. Laparoscopic implantation of electrodes for bilateral neuromodulation of the pudendal nerves and S3 nerve roots for treating pelvic pain and voiding dysfunction[J]. Int Urogynecol J, 2017, 15.doi: 10.1007/s00192-017-3411-7.[Epub ahead of print].
[47] Possover M. A novel implantation technique for pudendal nerve stimulation for treatment of overactive bladder and urgency incontinence[J]. J Minim Invasive Gynecol, 2014, 21(5): 888-892.
[48] Peters KM, Killinger KA, Boguslawski BM, et al. Chronic pudendal neuromodulation: expanding available treatment options for refractory urologic symptoms[J]. Neurourol Urodyn, 2010, 29(7): 1267-1271.
[49] Sanford MT, Suskind AM. Neuromodulation in neurogenic bladder[J]. Transl Androl Urol, 2016, 5(1): 117-126.
[50] Peters KM, Carrico DJ, Wooldridge LS, et al. Percutaneous tibial nerve stimulation for the long-term treatment of overactive bladder: 3-year results of the STEP study[J]. J Urol, 2013, 189(6): 2194-2201.
[51] Peters KM, Macdiarmid SA, Wooldridge LS, et al. Randomized trial of percutaneous tibial nerve stimulation versus extended-release tolterodine: results from the overactive bladder innovative therapy trial[J]. J Urol, 2009, 182(3): 1055-1061.
[52] Sirls ER, Killinger KA, Boura JA, et al. Percutaneous tibial nerve stimulation in the office setting: real world experience of over 100 patients[J]. Urology, 2017, 28. pii: S0090-4295(17)31224-4. doi: 10.1016/j.urology.2017.11.026.[Epub ahead of print]
[53] Scaldazza CV, Morosetti C, Giampieretti R, et al. Percutaneous tibial nerve stimulation versus electrical stimulation with pelvic floor muscle training for overactive bladder syndrome in women: results of a randomized controlled study[J]. Int Braz J Urol, 2017, 43(1): 121-126.
[54] Vecchioli-Scaldazza C, Morosetti C. Effectiveness and durability of solifenaci nversus percutaneous tibial nerve stimulation versus their combination for the treatment of women with overactive bladder syndrome: a randomized controlled study with a follow-up of ten months[J]. Int Braz J Urol, 2017, 24: 43. doi: 10.1590/S1677-5538.IBJU.2016.0611.[Epub ahead of print]
[55] de Groat WC, Yoshimura N. Pharmacology of the lower urinary tract[J]. Annu Rev Pharmacol Toxicol, 2001, 41: 691-721.
[56] Uy J, Yu M, Jiang X et al. Glutamatergic mechanisms involved in bladder overactivity and pudendal neuromodulation in cats[J]. J Pharmacol Exp Ther, 2017, 362(1): 53-58.
[57] McGee MJ, Danziger ZC, Bamford JA, et al. A spinal GABAergic mechanism is necessary for bladder inhibition by pudendal afferent stimulation[J]. Am J Physiol Renal Physiol, 2014, 307(8): 921-930.
[58] Xiao Z, Reese J, Schwen Z, et al. Role of spinal GABAA receptors in pudendal inhibition of nociceptive and nonnociceptive bladder reflexes in cats[J]. Am J Physiol Renal Physiol, 2014, 306(7): 781-789.
[59] Bandari J, Bansal U, Zhang Z, et al. Neurotransmitter mechanisms underlying sacral neuromodulation of bladder overactivity in cats[J]. Neuromodulation, 2017, 20(1): 81-87.
[1] 张秀琳. 膀胱内注射肉毒素治疗膀胱过度活动症的研究进展[J]. 山东大学学报 (医学版), 2018, 56(3): 12-18.
[2] 种铁,陈琦. 米拉贝隆治疗膀胱过度活动症的临床应用[J]. 山东大学学报 (医学版), 2018, 56(3): 6-11.
[3] 史本康. 膀胱过度活动症的诊断及治疗进展[J]. 山东大学学报 (医学版), 2018, 56(3): 1-5.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!