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山东大学学报（医学版） ›› 2014, Vol. 52 ›› Issue (7): 41-44.doi: 10.6040/j.issn.1671-7554.0.2014.154

• 基础医学 • 上一篇    下一篇

宾州毛耳叶苔化学成分研究

王姝麒1, 周金川1, 刘娜2, 张教真1, 王小宁1, 娄红祥1   

  1. 1. 山东大学药学院药物分析测试中心, 山东 济南 250012;
    2. 济南大学生物科学与技术学院制药工程系, 山东 济南 250002
  • 收稿日期:2014-03-23 修回日期:2014-06-12 出版日期:2014-07-10 发布日期:2014-07-10
  • 通讯作者: 王小宁。E-mail：wxn@sdu.edu.cn；娄红祥。E-mail：louhongxiang@sdu.edu.cn E-mail:wxn@sdu.edu.cn;louhongxiang@sdu.edu.cn
  • 基金资助:
    国家自然科学基金（81202422）；山东省自然科学基金（ZR2012HQ024）；山东大学自主创新基金

Chemical constituents from Jubula pennsylvanica Steph

WANG Shuqi1, ZHOU Jinchuan1, LIU Na2, ZHANG Jiaozhen1, WANG Xiaoning1, LOU Hongxiang1   

  1. 1. Drug Testing and Analysis Center, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, Shandong, China;
    2. Department of Pharmaceutical Engineering, School of Biological Science and Technology, Jinan 250002, Shandong, China
  • Received:2014-03-23 Revised:2014-06-12 Online:2014-07-10 Published:2014-07-10

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摘要： 目的 研究宾州毛耳叶苔Jubula pennsylvanica Steph.全草的化学成分。方法 采用硅胶柱色谱、凝胶柱色谱及制备高效液相色谱等方法对宾州毛耳叶苔乙醇提取物的乙醚部位进行分离纯化，根据波谱数据结合理化性质鉴定化合物结构。结果 从宾州毛耳叶苔中分离得到 5个化合物，分别鉴定为核木子素E（1）、片叶苔素D（2）、地钱素C（3）、异地钱素C（4）和半月苔素（5）。结论 化合物 1～5 为首次从毛耳叶苔属植物中分离得到。

关键词: 核木子素E, 片叶苔素D, 半月苔素, 毛耳叶苔属, 宾州毛耳叶苔

Abstract: Objective To study the chemical constituents of Jubula pennsylvanica Steph.. Methods The chemical constituents from the diethyl ether fraction of ethanol extract from Jubula pennsylvanica Jubula Steph. were isolated and purified by various chromatographic methods, including silica gel, Sephadex LH-20 columns, and semi-preparation HPLC. Structures of the isolated compounds were elucidated based on NMR and MS data, as well as by comparison with the previous data. Results Five compounds were obtained from Jubula pennsylvanica Steph. and identified as perrottetin E(1), riccardin D(2), marchantin C(3), isomarchantin C(4), and lunularin(5). Conclusion Compounds 1-5 are isolated from the plants in genus Jubula for the first time.

Key words: Jubula, Perrottetin E, Lunularin, Jubula pennsylvanica Steph., Riccardin D

中图分类号: 

  • R93
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