关键词: 腺瘤性息肉, 高危人群, 复发因素, 随访

Abstract:

Objective  To investigate the correlative factors for the recurrence of adenomatous polyps after endoscopic treatment so as to screen out high risk people and to provide information for proper surveillance. Methods  The data of the adenoma recurrence among patients undergone endoscopic polypectomy from January 2000 to March 2013 were retrospectively reviewed. Univariate χ2 test and multivariate logistic regression analysis were performed to analyze the association between risk factors and adenoma recurrence. Results  A total of 249 cases (26.83%) developed new adenomas during the follow-up. Univariate analysis indicated that adenoma recurrence was associated with age, number of adenomas, adenoma diameter, location, pathological type, grade of dysplasia, basilar part and treatment method, but not with gender. Logistic regression analysis revealed that age, number of adenomas, adenoma diameter, pathological type, grade of dysplasia, and basilar part were independent risk factors of adenoma recurrence whereas adenoma location and treatment method were not. Conclusion  Patients aged 60 years, with adenoma number ≥3, diameter > 10mm, villous, high grade of dysplasia and sessile adenoma, have high risk of adenoma recurrence. Adenomas tend to recur in patients with more risk factors; therefore, intensive surveillance is recommended.

Key words: Recurrence factor, High-risk group, Surveillance,  Adenomatous polyp