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山东大学学报(医学版) ›› 2013, Vol. 51 ›› Issue (4): 55-58.

• 临床医学 • 上一篇    下一篇

手术夹闭和血管内介入治疗颅内宽颈动脉瘤的疗效比较

王卫1,2,王志刚1,丁璇1,王洪亮2,谢永胜2   

  1. 1.山东大学第二医院神经外科,  济南 250033; 2. 武警山东总队医院神经外科, 济南 250014
  • 收稿日期:2012-11-12 出版日期:2013-04-10 发布日期:2013-04-10
  • 通讯作者: 王志刚(1962- ),男,教授,博士生导师,主要从事脑肿瘤及脑血管病的研究。 E-mail:wzg1110@126.com
  • 作者简介:王卫(1980- ),男,硕士研究生,医师,主要从事脑血管病临床与基础研究。 E-mail:710078818@qq.com
  • 基金资助:

    山东省科技计划项目(2008GG10002060)

Efficacy comparison of clipping and endovascular treatment for wide-necked intracranial aneurysms

WANG Wei1,2, WANG Zhi-gang1, DING Xuan1, WANG Hong-liang2, XIE Yong-sheng2   

  1. 1. Department of Nuerosurgery, the Second Hospital of Shandong University, Jinan 250033, China;
    2. Department of Nuerosurgery, Shandong General Hospital of CAPF, Jinan 250014, China
  • Received:2012-11-12 Online:2013-04-10 Published:2013-04-10

摘要:

目的   探讨颅内宽颈动脉瘤不同治疗方法的疗效。方法   回顾性分析2008年5月至2011年7月间手术夹闭和血管内介入治疗的146例、152个颅内宽颈动脉瘤,比较其术后疗效。预后采取改良mRS评分,0~2分为良好,3~6分为不良。结果   手术夹闭90例患者94个动脉瘤,随访3~24个月(平均12.5个月),未见复发。其中完全夹闭92个,夹闭不全2个,予以再次手术夹闭,良好79例(87.8%)。血管内介入治疗56例、58个动脉瘤,随访6~96个月(平均36.2个月),复发8个(13.8%),良好50例(89.2%)。两组预后差异无统计学意义(P>0.05)。结论   手术夹闭和血管内介入治疗均能有效治疗颅内宽颈动脉瘤。手术夹闭不易复发,血管内介入治疗相对容易复发。

关键词: 宽颈动脉瘤;手术夹闭;血管内介入治疗;预后

Abstract:

ObjectiveTo discuss the curative effects of treating wide-necked intracranial aneurysms with different methods. MethodsWe retrospective analyzed 146 patients with a total of 152 wide-necked intracranial aneurysms which underwent surgical clipping and endovascular treatment from May 2008 to July 2011.The postoperative effectiveness was compared. The modified Rankin Scale(mRS) was used to evaluate the outcome. The mRS score =0-2 was defined as good outcome and the mRS score =3-6 score was defined as poor outcome. Results90 patients with 94 aneurysms were treated with surgical clipping.The followingup results of 3 to 24 mohths(mean 12.5 months)showed that there was no recurrence in all aneurysms. 92 aneurysms were clipped completely and 2 were clipped incompletely.The latter were clipped again.79 patients (87.8%) had good outcome. 56 patients with 58 aneurysms underwent endovascular treatment. The following-up results of 6 to 96 months(mean 36.2 months)showed that 8 recurrence aneurysms(13.8%). 50 patients (89.2%) had good outcome. The outcome of the two groups did not differ significantly(P>0.05). ConclusionBoth surgical clipping and endovascular treatment can treat wide-necked intracranial aneurysms effectively. Lower recurrence was associated with surgical clipping,but higher recurrence was associated with endovascular treatment in wide-necked intracranial aneurysms.

Key words: Wide-necked intracranial aneurysms; Surgical clipping; Endovascular treatment; Outcome

中图分类号: 

  • R605
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