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山东大学学报(医学版) ›› 2013, Vol. 51 ›› Issue (1): 98-102.

• 临床医学 • 上一篇    下一篇

宁阳县城乡居民高血压患者视网膜病变现况分析

栗映梅1,2,吴欣怡1,王玉2,范传峰2,盛艳娟2,舒相汶2,陈璇2,吴昌龙2    

  1. 1.山东大学齐鲁医院眼科, 济南 250012; 2.济南市第二人民医院眼科, 济南 250001
  • 收稿日期:2012-09-10 出版日期:2013-01-10 发布日期:2013-01-10
  • 通讯作者: 吴欣怡(1956- ),女,主任医师,博士生导师,主要从事眼科疾病研究。 E-mail: xywu8868@163.com
  • 作者简介:栗映梅(1977- ),女,博士研究生,主治医师,主要从事眼科疾病研究。 E-mail: liyingmei77@sohu.com
  • 基金资助:

    山东省医药卫生科技发展计划(2009HD002)

Epidemiological investigation of hypertensive retinopathy in residents of Ningyang county in the Shandong province

LI Ying-mei1,2, WU Xin-yi1, WANG Yu2, FAN Chuan-feng2, SHEN Yan-juan2,SHU Xiang-wen2, CHEN Xuan2, WU Chang-long2   

  1. 1.  Department of Ophthalmology,Qilu Hospital of Shandong University, Jinan 250012, China;
    2. Department of Ophthalmology, Jinan  Second  People’s  Hospital, Jinan 250001, China
  • Received:2012-09-10 Online:2013-01-10 Published:2013-01-10

摘要:

目的   了解山东省宁阳县城乡居民中高血压视网膜病变(HR)的患病率,分析其相关危险因素。方法   采用整群随机抽样方法,抽取宁阳县城区和农村部分35岁以上居民进行血压测量、问卷调查、眼科检查及静脉血实验室检测。结果   1086例(81.78%)高血压患者完成了全部的问卷调查、体格检查和实验室检测。其中313例眼底正常,783例存在不同程度的HR,患病率为71.18%,其中Ⅰ期532例(68.82%),Ⅱ期159例(20.57%),Ⅲ期79例(10.22%),未发现Ⅳ期HR。53例(6.86%)出现眼部并发症。1086名高血压患者中,知道自己患高血压病变的占79.1%(859人),曾经接受药物治疗的占31.5%(342人)。农村居民HR患病率为73.68%,城区居民HR患病率为64.82%,前者明显高于后者。HR的患病率随着患者的年龄、血压值以及高血压病程的增加而升高,与患者的性别没有明显相关性。经有序logistic回归分析,年龄、城乡差别、高血压病程等是HR的危险因素。混合型高血压者HR患病率是血压值正常的2.44倍,高血压病程10年以上者HR患病率是病程1年以下者的4.15倍。结论   宁阳县城乡居民HR患病率较高,血压、年龄、城乡差别、高血压病程等是其相关的危险因素,存在对疾病的知晓率低、治疗率低且不规范、控制率低的情况。建立HR的立体防治体系需要眼科与社区、基层医疗机构以及各级卫生机构在不同层面上的密切协作。

关键词: 高血压视网膜病变;患病率;危险因素;流行病学

Abstract:

Objective   To explore the morbidity of hypertensive retinopathy (HR)in the residents of Ningyang county in the Shandong province and to analyze its related risk factors. Methods   Some residents over 35 years old in the Ningyang county were selected by a cluster random sampling method and investigated with questionnaire surveys, physical  examination  and venous blood tests. Results   1086(81.78%) hypertension patients completed all of the questionnaire, physical examination and laboratory detection. There were 313 patients with normal retinal and 783 with hypertensive retinopathy in varying degrees, including 532 cases of gradeⅠ(68.82%),159 cases of grade Ⅱ(20.57%), 79 cases of grade Ⅲ (10.22%) and none of grade Ⅳ, and  only  53 cases occurred ocular complications (6.86%). The morbidity of HR in Ningyang county was 71.18%. 859 patients knew that they were suffering from high blood pressure diseases (79.1%) and 342 had been treated with drug therapy (31.5%). The morbidity of HR in the rural residents was 73.68%, which was clearly higher than that in county residents (64.82%). With the increase of patient’s age, blood pressure value and the course of the  disease, the morbidity of HR was increased, but there was no significant correlation with the gender of the patients. By ordinal logistic regression analysis, age, rural area, and the course of hypertension were risk factors of HR. The severity of HR in patients with mix-type hypertension(sbp≥140 and dbp≥90) was 2.44 times than that of the normal blood pressure group. The severity of HR with the group over 10-years hypertension course was 4.15 times than that of the group of the course <1 year. Conclusion   The morbidity of hypertensive retinopathy in Ningyang county is relatively high. The risk factors include blood pressure, age, residential area,and the course of hypertension. And it is characterized with low awareness rate , low treatment rate and low control rate. Ophthalmologists need close cooperation with medical institutions at all levels to establish  the  prevention and control system of HR.

Key words: Hypertensive retinopathy;  Morbidity; Risk factors; Epidemiology

中图分类号: 

  • R774
[1] 毕宏生1,潘华伟2,刘力1, 沙晓娟4,张媛3,潘雪梅1,王束玫4. 糖尿病及其合并视网膜病变者特质应对方式分析[J]. 山东大学学报(医学版), 2011, 49(10): 146-149.
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