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山东大学学报(医学版) ›› 2013, Vol. 51 ›› Issue (1): 71-74.

• 临床医学 • 上一篇    下一篇

应用食管多通道腔内阻抗观察不同体质量指数反流性食管炎患者的反流特点

宋璇,郝洪升,吕国苹,孙莉娟,陆晓恒   

  1. 山东大学齐鲁医院消化内科, 济南 250012
  • 收稿日期:2012-06-04 出版日期:2013-01-10 发布日期:2013-01-10
  • 通讯作者: 郝洪升(1963- ),男,教授,主要从事功能性消化系统疾病的治疗与研究。 E-mail: haohongsheng63@126.com
  • 作者简介:宋璇(1986- ),女,硕士研究生,主要从事功能性消化系统疾病的研究。 E-mail: songxuan0207@163.com

Observation of the reflux characteristics of reflux esophagitis in patients with different body mass indexes using multichannel intraluminal impedance

SONG Xuan, HAO Hong-sheng, L Guo-ping, SUN Li-juan, LU Xiao-heng   

  1. Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan 250012, China
  • Received:2012-06-04 Online:2013-01-10 Published:2013-01-10

摘要:

目的   应用多通道腔内阻抗技术联合24h pH监测(MII-pH)观察不同体质量指数(BMI)的反流性食管炎(RE)患者的反流特点。方法   将56例RE患者按照BMI分为正常组、超重组和肥胖组。通过多通道腔内阻抗联合pH监测,观察各研究对象反流相关指标,并对pH监测及阻抗结果进行统计分析。结果   与正常组相比,超重组、肥胖组在总体、直立位和仰卧位pH<4时间百分比、酸反流次数和液体反流次数上有统计学差异(P<0.05或0.01),超重组和肥胖组间无统计学差异(P均>0.05)。3组在弱酸反流、非酸反流、混合反流、气体反流、近端反流方面均无统计学差异(P均>0.05)。结论   超重和肥胖患者更容易发生酸暴露、酸反流和液体反流,但肥胖程度对酸暴露、酸反流和液体反流的影响无明显差异。

关键词: 多通道腔内阻抗;pH监测;体质量指数;反流性食管炎;超重;肥胖

Abstract:

Objective   To observe the reflux characteristics of patients with reflux esophagitis in different body mass indexes using combined multichannel intraluminal impedance-pH (MII-pH) monitoring.  Methods   56 patients with reflux esophagitis were enrolled and divided into the normal group, overweight group and obesity group according to their body mass indexes. We observed reflux-related indicators of individuals with MII-pH monitoring, and then performed statistical analysis on pH monitoring and impedance results. Results   Compared with normal group, there were significant differences in overweight group and obesity group on percent time pH<4 (total, upright and recumbent), acid reflux and liquid reflux (P<0.05 or 0.01),while no significant differences were found between overweight and obesity groups (all P>0.05). There were no significant differences in weakly acid reflux, non-acid reflux, mixed reflux, gas reflux and proximal reflux episodes among the three groups (all P>0.05). Conclusion   There are more acid exposure, acid reflux and liquid reflux episodes in overweight and obese patients; however, the effect of the extent of obesity on acid exposure, acid reflux and liquid reflux has no significant difference.

Key words: Multichannel intraluminal impedance; pH monitoring; Body mass index; Reflux esophagitis; Overweight; Obesity

中图分类号: 

  • R571
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