老年直肠癌与非老年直肠癌临床病理特征比较

山东大学学报(医学版) ›› 2011, Vol. 49 ›› Issue (8): 120-.

老年直肠癌与非老年直肠癌临床病理特征比较

张彬彬1，陈甜甜2，王国昌2，吕明3

山东大学 1.齐鲁医院普外科； 2.公共卫生学院流行病与卫生统计学研究所；
3.齐鲁医院科研处，济南 250012

收稿日期:2011-03-10 出版日期:2011-08-10 发布日期:2011-08-10
通讯作者: 吕明(1970- )，女，教授，主要从事慢性非传染性疾病的流行病学研究。 E-mail: lu.ming528@gmail.com
作者简介:张彬彬(1974- )，女，硕士研究生，主要从事结直肠癌防治方面研究。

Comparison of clinicopathological characteristics of rectal cancer between elderly and young patients

ZHANG Binbin1, CHEN Tiantian2, WANG Guochang2, L Ming3

1. Department of General Surgery, Qilu Hospital of Shandong University, Jinan 250012, China;
2. Department of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China;
3. Department of Science Research, Qilu Hospital of Shandong University, Jinan 250012, China

Received:2011-03-10 Online:2011-08-10 Published:2011-08-10

摘要/Abstract

摘要：

目的对比分析老年和非老年直肠癌的临床病理特征，提高对老年直肠癌的认识及诊治水平。方法收集2010年1月至9月山东大学齐鲁医院收治的117例直肠癌患者，根据年龄分为两组：老年组：>60岁；非老年组：≤60岁。分析老年直肠癌患者发病情况同非老年直肠癌患者的差异。结果老年组低位直肠癌(肿瘤下缘距肛门距离<5cm)发病率(32.31%)小于非老年组(54.90%)，差异有统计学意义(P=0.0145)。两组患者临床症状出现时间以2周～2年为主，占87.07%。老年组淋巴结转移率(50.88%)高于非老年组(29.79%)，差异有统计学意义(P=0.0297)。16.39%的老年患者出现术后并发症，高于非老年组(2.04%)，差异有统计学意义(P=0.0214)。结论患者确诊前症状持续时间长，应加强癌症知识宣传，提高患者防癌意识，进而提高肿瘤的早期诊断。加强术前合并症的处理及术前术后的护理工作，以减少术后并发症，并建立筛查制度以从根本上预防。

关键词: 直肠癌；老年；临床病理特征

Abstract:

Objective To compare clinicopathological characteristics between elderly and young patients with rectal cancer in order to improve awareness and diagnosis of elderly rectal cancer. Methods A total of 117 patients with rectal cancer treated between January 2010 and September 2010 were divided into the elderly group (>60 years old), and the young group (≤60 years old). Clinicopathological characteristics of the two groups were analyzed. Results Elderly patients had a significant smaller ratio(32.31%) of low rectal neoplasm (distance from the anus<5cm) than young patients(54.90%) (P=0.0145). Clinical symptoms mainly appeared from 2 weeks to 2 years before diagnosis, accounting for 87.07%. The ratio of lymph node metastasis was markedly higher in the elderly group than in the young group (50.88% vs 29.79%, P=0.0297). Elderly patients(16.39%) were more likely to have complications than young patients(2.04%) (P=0.0214). Conclusion Clinical symptoms last a long time before patients are diagnosed with rectal cancer. Patients should increase awareness of health to improve the early diagnosis of rectal cancer. More healthcare should be given to elderly patients before and after surgery to reduce postoperative complications. Colorectal cancer screening system should be established in China to reduce the incidence

Key words: Rectal cancer; Elderly; Clinical pathological characteristics

中图分类号:

R735.37

张彬彬1，陈甜甜2，王国昌2，吕明3. 老年直肠癌与非老年直肠癌临床病理特征比较[J]. 山东大学学报(医学版), 2011, 49(8): 120-.

ZHANG Binbin1, CHEN Tiantian2, WANG Guochang2, L Ming3. Comparison of clinicopathological characteristics of rectal cancer between elderly and young patients[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2011, 49(8): 120-.

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