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山东大学学报(医学版) ›› 2011, Vol. 49 ›› Issue (2): 128-.

• 论文 • 上一篇    

济南市城市居民慢性阻塞性肺病现状调查及相关危险因素分析

王川,马德东,肖伟,张玉可,姜园园,何宝龙, 张一,王洪超,许霞, 季秀丽,王琴,王得翔,孙丛丛, 陈宏礼,吴瑕   

  1. 山东大学齐鲁医院呼吸内科,  济南  250012
  • 收稿日期:2010-04-09 出版日期:2011-02-10 发布日期:2011-02-10
  • 通讯作者: 肖伟,女,博士,教授,博士生导师,主要从事COPD及肺癌研究。 E-mail:xiaowei4226@163.com
  • 作者简介:王川(1978- ),男,硕士研究生,住院医师,主要从事COPD研究;马德东(1976- ),男,博士,主治医师,硕导,主要从事肺癌及COPD研究,并列第一作者。

Epidemiological status and related risk factors of COPD in  urban residents in Jinan

WANG Chuan, MA De-dong, XIAO Wei, ZHANG Yu-ke, JIANG Yuan-yuan, HE Bao-long, ZHANG Yi, WANG Hong-chao, XU Xia, JI Xiu-li, WANG Qin, WANG De-xiang, SUN Cong-cong, CHEN Hong-li, WU Xia   

  1. Department of Respiratory, Qilu Hospital of Shandong University, Jinan 250012, China
  • Received:2010-04-09 Online:2011-02-10 Published:2011-02-10

摘要:

目的     获得济南城市居民慢性阻塞性肺疾病(COPD)患病率,了解COPD的诊治现状,分析COPD相关危险因素。方法    采用横断面多级抽样的方法,对济南市城区内年龄≥40岁的人群进行调查。被调查者填写调查问卷 (参考GOLD委员会COPD负担研究专题的流行病学调查问卷,结合我国国情制定统一问卷),应用CHEST-HI801便携式肺功能仪对被调查者进行肺通气功能测定,参照中华医学会呼吸病学分会制定的COPD诊治指南(2007年修订版),确定诊断。结果    按规则抽样应该调查的人数为2467人,实际完成调查问卷和肺通气功能检查者为2055人;符合COPD诊断者为156例,总体患病率为7.6%,男性患病率为12.2%(111/156),女性患病率为3.9%(45/156);156例COPD患者中既往已被确诊有84例(53.8%),其中无正规治疗者37例(44.0%),之前从未诊断者72例(46.1%),无临床症状者48例(30.8%);应用多因素Logistic回归分析,影响COPD患病的主要因素有:吸烟,男性,高龄,低收入及呼吸病家族史。结论    济南市40岁以上城市居民COPD的总体患病率为7.6%,其诊断和治疗现状远不能令人满意,COPD的相关危险因素涉及个体、家庭和社会多个方面。

关键词: 肺疾病,慢性阻塞性;危险因素;流行病学

Abstract:

Objective    To obtain the prevalence of chronic obstructive pulmonary disease (COPD) in urban residents in Jinan, to learn the status of diagnosis and treatment and to explore the possible related risk factors.   Methods    A cross-sectional study with a multistage stratified random sampling method was performed to select subjects aged ≥ 40 years. A questionnaire, designed with reference to the epidemiological questionnaire made by the program of COPD burden of GOLD committee and the practical situation of China, was used in interviews of the subjects. Then the CHEST HI-801 spirometer was used to test lung function in those who finished the questionnaire. The diagnosis of COPD was based on the standard made by the COPD group of Chinese Medical Association (2007 version). Results    According to the sampling rule, 2467 subjects should be included, among whom 2055 subjects finished the questionnaire and spirometry. The overall prevalence of COPD in urban residents in Jinan was 7.6%(156/2055), 12.2%(111/156) in males and3.9%(45/156) in females. 84 cases had been confirmed, in which only 37 (44.0%) cases accepted regular treatment,  and 48(30.8%) cases were asymptomatic. Multivariate logistic regression analysis found that the main factors affecting the state of COPD were smoking, males, senility, low income and a family history of respiratory diseases.  Conclusion    The overall prevalence of COPD in urban residents aged ≥ 40 years in Jinan was 7.6%. The actual state of diagnosis and treatment is far from satisfactory. Risk factors of COPD are related to individuals, family, and society.

Key words: Pulmonary disease, chronic obstructive; Risk factors; Epidemiology

中图分类号: 

  • R563
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