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山东大学学报(医学版) ›› 2011, Vol. 49 ›› Issue (10): 18-22.

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Modulation of DC function by NKT cells

YANG  Xi   

  • 收稿日期:2011-07-30 出版日期:2011-10-10 发布日期:2011-10-10
  • 作者简介:杨熙, 山东潍坊人, 早年毕业于潍坊二中。 原山东医科大学77级本科生、82级研究生,分获医学学士、硕士学位。1989年初赴加拿大曼尼托巴大学留学, 获免疫学博士学位。

  1. Laboratory for Infection and Immunity, Departments of Medical Microbiology and Immunology, Faculty of Medicine,
    University of Manitoba, Winnipeg, Manitoba R3E 0W3, Canada
  • Received:2011-07-30 Online:2011-10-10 Published:2011-10-10

Abstract:

Both dendritic cells (DC) and natural killer T (NKT) cells are small cell populations related to immune regulation. The interaction between these two types of immune cells is a hot topic in current study on immunobiology. Recent data not only demonstrate that DC can  influence the activation/function of NKT cells but also suggest that NKT cells can feedback on DC, thus modulating the phenotype and function of DC. This twoway interaction between NKT cells and DC may play an important role in the linkage of innate and adaptive immune responses.

Key words: Dendritic cells;  NKT cells; Infection1

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