关键词: 激光治疗；药物治疗；复发性口腔溃疡

Abstract:

Objective    To evaluate the effect of 660nm laser on treating recurrent oral ulcer (ROU).  Methods    A total of 121 ROU patients (gravistype excluded) were divided into two groups: the experimental group with 61patients and the control group with 60 patients. The experimental group received laser therapy and the control group received drug treatment with Jinda glycerol. The evaluation criteria were DP classification and P-VAS grading. Pain indexes(P) and mean ulcer duration(D) were recorded before treatment, and 3minutes, 5 minutes, 10 minutes and 24 hours after treatment. The results were analyzed by using ttest and χ2 analysis. Results    There were significant differences in the pain relief rate between the two groups 3 minutes, 10 minutes and 24 hours after treatment（P＜0.05）,  while there was no difference at baseline and 5 minutes after treatment（P>0.05）. There were significant differences in the total effective rate between the two groups （P＜0.05）. Conclusions    660nm laser is more effective in the treatment of ROU compared with the drug, with earlier onset of action and longer duration. It can obviously accelerate healing time and relieve pain.

Key words: Laser therapy; Drug treatment; Recurrent oral ulcer