人格特质对抑郁症患者临床疗效的影响

山东大学学报(医学版) ›› 2010, Vol. 48 ›› Issue (12): 138-142.

人格特质对抑郁症患者临床疗效的影响

赵蕾1,焦志安2, 陈伊莎3，赵国庆2

1.山东大学医学院, 济南 250012; 2. 山东大学附属省立医院临床心理科, 济南 250021；
3.山东中医药大学，济南 250355

收稿日期:2010-08-17 发布日期:2010-12-16
通讯作者: 焦志安（1964- ）,男,副教授,主要从事心境障碍研究。E-mail: jiaozhian@126.com
作者简介:赵蕾（1985- ）,女,硕士研究生,主要从事心境障碍研究。

Influence of personality traits on clinical outcomes in depressive patients

ZHAO Lei1, JIAO Zhi-an2, CHEN Yi-sha3， ZHAO Guo-qing2

1. School of Medicine, Shandong University, Jinan 250012, China;
2. Department of Clinical Psychology, Shandong Provincial Hospital Affiliated to
Shandong University, Jinan 250021, China;
3. Shandong University of Traditional Chinese Medicine， Jinan 250355, China

Received:2010-08-17 Published:2010-12-16

摘要/Abstract

摘要：

目的探讨抑郁症患者的人格特质对临床疗效的影响。方法采用NEO个性问卷对72例抑郁症患者和67例正常对照者进行测试，病例组给予艾司西酞普兰治疗8周，采用汉密尔顿抑郁量表和汉密尔顿焦虑量表在治疗前后评估病例组的抑郁严重程度。结果抑郁症患者在多个人格维度和特质层面上与正常对照者之间存在统计学差异(P＜0.05),并且抑郁严重程度与N1显著相关(r=0.415)。在NEO个性问卷中N1、N3、C、C3与抑郁症患者治疗8周末汉密尔顿抑郁量表减分率明显相关。结论抑郁症患者与正常人人格特质有明显差异。人格特质可以预测抑郁症患者的临床疗效。

关键词: NEO个性问卷；人格；抑郁

Abstract:

Objective To explore the impact of personality traits of depressive patients on clinical outcomes. Methods Personality traits were evaluated with the Revised NEO Personality Inventory（NEO-PI-R） in depressive outpatients(n=72) and the controls(n=67). The patients were treated with escitalopram for 8 weeks. Severity of depression was assessed before and after treatment by Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA). Results The patients with depression had a significantly different personality profile at the baseline compared with the healthy controls(P＜0.05) and the severity of their illness correlated with high scores in anxiety facet(N1)(r=0.415). The NEO-PI-R showed that N1, N3, C and C3 were strongly associated with score reduced rates of HAMD at the end of 8th week. Conclusion There are significant differences in personality traits between depressive patients and healthy controls. Personality traits may predict the clinical outcome in depressive patients.

Key words: NEO Personality Inventory; Personality; Depression

中图分类号:

R-749

赵蕾1,焦志安2, 陈伊莎3，赵国庆2 . 人格特质对抑郁症患者临床疗效的影响[J]. 山东大学学报(医学版), 2010, 48(12): 138-142.

ZHAO Lei1, JIAO Zhi-an2, CHEN Yi-sha3， ZHAO Guo-qing2. Influence of personality traits on clinical outcomes in depressive patients [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2010, 48(12): 138-142.

参考文献

多维度评价

Viewed

Full text

Abstract

Cited

Shared

Discussed