磁共振弥散张量成像对轻度脊髓型颈椎病的诊断价值

山东大学学报(医学版)

磁共振弥散张量成像对轻度脊髓型颈椎病的诊断价值

孟祥水¹，柴相君²，李笃民¹，马祥兴¹，李传福¹，侯金文¹

山东大学齐鲁医院 1. 放射科； 2. 耳鼻喉科，济南 250012

收稿日期:2008-04-14 修回日期:1900-01-01 出版日期:2008-09-16 发布日期:2008-09-16
通讯作者: 侯金文

Diagnosis value of DTI in cervical spondylosis in early stages

MENG Xiang-shui¹, CHAI Xiang-jun², LI Du-min¹, MA Xiang-xing¹, LI Chuan-fu¹, HOU Jin-wen¹

1. Department of Radiology; 2. Department of Otolaryngolgogy, Qilu Hospital of Shandong University, Jinan 250012, China

Received:2008-04-14 Revised:1900-01-01 Online:2008-09-16 Published:2008-09-16
Contact: HOU Jin-wen

摘要/Abstract

摘要： 目的探讨3.0T磁共振DTI技术对无信号改变脊髓型颈椎病的诊断价值。方法选择21例健康志愿者作为对照组和42例无T2信号改变的脊髓型颈椎病患者行颈髓DTI成像，根据患者有无颈椎病体征将其分为阴性体征组（A组）和阳性体征组（B组）。分析各组表观弥散系数(ADC)、分数各向异性值(FA)、平行于颈髓长轴、前后径和左右径本征值λ₁、λ₂、λ₃值的变化。结果所有受检者DTI成像显示满意。对照组颈髓平均ADC值为（0.78±0.08）×10^-3mm²/s，FA值为0.72±0.03，λ₁、λ₂、λ₃值分别为（1.51±0.15）×10^-3、（0.42±0.09）×10^-3、（0.41±0.10）×10^-3mm²/s。A组FA值大于B组（P＜0.01）,B组ADC、λ₁、λ₂、λ₃值均大于A组（P＜0.05）；对照组与A组比较，ADC、FA、λ₁值无统计学差异（P＞0.05），A组λ₂、λ₃值大于对照组（P＜0.05）；对照组FA值大于B组（P＜0.01），B组ADC、λ₂、λ₃值大于对照组（P＜0.05），而对照组和患者组间λ₁值无统计学差异（P＞0.05）。结论ADC、FA、λ₁、λ₂、λ₃值是检测脊髓型颈椎病早期颈髓微结构改变的敏感指标。

关键词: 脊髓型颈椎病, 弥散张量成像, 磁共振成像

Abstract: To evaluate the diagnosis value of diffusion tensor imaging (DTI) in cervical spondylosis without high signal intensity on the compression sites. MethodsTwenty-one healthy volunteers and 42 patients with cervical spondylosis without high signal intensity on the T2WI were subjected to DTI by using a 3.0T MR scanner. Forty-two patients were divided into 2 groups based on having or not having cervical spondylosis symptoms. Patients in group A had symptoms of cervical spondylosis while patients in group B did not. ADC, FA, λ₁, λ₂ and λ₃ values were analyzed with a software package of SPSS 11.0. Fiber tracking was performed on examinees with Functool software of the GE Company. ResultsHigh quality ADC maps, FA maps and fiber tracking of cervical spinal cords were obtained. For healthy subjects, average ADC, FA, λ₁, λ₂ and λ₃ values were (0.78±0.08)×10^-3mm²/s, 0.72±0.03, (1.51±0.15)×10^-3mm²/s, (0.42±0.09)×10^-3mm²/s and (0.41±0.10)×10^-3mm²/s respectively. The FA value of group A was higher than that of group B（P＜0.01）, while values of ADC, FA, λ₁, λ₂ and λ₃ of group B were higher than those of group A（P＜0.05）. The ADC, FA and λ₁ values were not statistically significant between group A and the control group（P＞0.05）, while values of λ₂ and λ₃ of group A were higher than those of the control group（P＜0.05）. The FA value of the control group was higher than that of group B（P＜0.01）, and the ADC, λ₂ and λ₃ values of group B were higher than those of the control group （P＜0.05）, while there were no statistically significant differences between group B and the control group（P＞0.05）. ConclusionThe ADC, FA, λ₁, λ₂ and λ₃ values are sensitive indices for evaluation of the subtle structure of cervical spinal cords which can be quantitatively analyzed by DTI in the early stage of cervical spondylosis.

Key words: Magnetic resonance imaging, Diffusion tensor imaging, Cervical spondylosis

中图分类号:

R445.2

孟祥水,柴相君,李笃民,马祥兴,李传福,侯金文 . 磁共振弥散张量成像对轻度脊髓型颈椎病的诊断价值[J]. 山东大学学报(医学版), 2008, 46(9): 873-876.

MENG Xiang-shui,CHAI Xiang-jun,LI Du-min,MA Xiang-xing,LI Chuan-fu,HOU Jin-wen. Diagnosis value of DTI in cervical spondylosis in early stages[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2008, 46(9): 873-876.

参考文献

相关文章 15

[1]	王玉红,张丽红,王林省,陈月芹,王彦辉,王皆欢,李传福. 消化道颗粒细胞瘤的影像学表现[J]. 山东大学学报（医学版）, 2017, 55(8): 66-70.
[2]	张华,庄霞,刘振东,刁玉涛,杜佳晨,崔谊. 磁共振弥散张量成像技术评价高血压对年轻成年人脑白质损伤[J]. 山东大学学报（医学版）, 2017, 55(5): 56-60.
[3]	许玉军,柳明,何祥萌,李成利. 1.0T开放型磁共振引导经皮穿刺¹²⁵I放射性粒子植入治疗晚期胰腺癌[J]. 山东大学学报（医学版）, 2017, 55(2): 21-25.
[4]	王光彬. MRI在凶险性前置胎盘诊断中的价值[J]. 山东大学学报（医学版）, 2016, 54(9): 7-9.
[5]	董金叶,林祥涛,曹金凤,吴勇,赵慧,谢辉辉,肖连祥. 16~42周胎儿脊髓颈膨大发育的MRI分析[J]. 山东大学学报（医学版）, 2016, 54(5): 74-78.
[6]	张湛,许相丰,刘海东,王玮. MRI在宫颈癌T分期中的诊断价值[J]. 山东大学学报（医学版）, 2016, 54(5): 70-73.
[7]	俞璐,刘强. 体素内不相干运动磁共振成像对糖尿病患者肾脏功能的评价作用[J]. 山东大学学报（医学版）, 2016, 54(11): 68-71.
[8]	董芳,杜怡峰. 腔隙性脑梗死患者认知障碍与高同型半胱氨酸血症、梗死灶数目及体积的相关性[J]. 山东大学学报（医学版）, 2016, 54(10): 46-49.
[9]	孟祥水,柴相君,马祥兴,任庆国,杨志成. CT、MRI对喉癌治疗方案选择的价值[J]. 山东大学学报（医学版）, 2016, 54(10): 76-79.
[10]	张扬, 李万湖, 宋惟阳, 刘春蕾, 张权. 健康中老年人脑血管反应能力分布特征的屏气功能磁共振成像研究[J]. 山东大学学报（医学版）, 2015, 53(5): 85-88.
[11]	翟栋材, 张申杰, 张博, 张涛. 超声造影与增强MRI评价聚焦超声消融治疗子宫腺肌症的对照研究[J]. 山东大学学报（医学版）, 2014, 52(S1): 112-113.
[12]	Hasan Akhtar, 王茜，李传福. 中枢神经系统表面含铁血黄素沉积症的影像表现(附1例报道)[J]. 山东大学学报（医学版）, 2014, 52(5): 111-112.
[13]	郝雯，赵斌，王翠艳，李慧华，邱秀玲. 乳腺MRI在预测导管内癌早期浸润中的价值[J]. 山东大学学报（医学版）, 2014, 52(4): 102-106.
[14]	郭卫华, 赵素红, 庞国栋, 邵广瑞. 磁共振弥散加权成像评估肝细胞癌组织学分级的价值[J]. 山东大学学报（医学版）, 2014, 52(12): 89-93.
[15]	王音1，陶国伟1，耿群1，王茜2，马喆1，刘韶平1，李扬3，潘秋丽4. 超声联合MRI诊断胎儿大脑皮层发育异常的研究[J]. 山东大学学报（医学版）, 2014, 52(1): 57-61.

多维度评价

Viewed

Full text

Abstract

Cited

Shared

Discussed