正畸治疗中龈沟液天冬氨酸转氨酶、碱性磷酸酶水平的变化

山东大学学报(医学版)

正畸治疗中龈沟液天冬氨酸转氨酶、碱性磷酸酶水平的变化

任旭升¹，王旭霞¹，张文娟²，徐建光¹，张君¹

1. 山东大学口腔医学院正畸科，济南 250012； 2. 山东中医药大学附属医院口腔科，济南 250013

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-08-16 发布日期:2008-08-16
通讯作者: 张君

Changes of the AST and ALP levels in gingival crevicular fluid during orthodontics treatment

REN Xu-sheng¹, WANG Xu-xia¹, ZHANG Wen-juan², XU Jian-guang¹, ZHANG Jun¹

1. Department of Orthodontics， School of Stomatology， Shandong University， Jinan 250012, China; 2. Department of Stomatology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250013, China

Received:1900-01-01 Revised:1900-01-01 Online:2008-08-16 Published:2008-08-16
Contact: ZHANG Jun

摘要/Abstract

摘要：

目的〓〖HTK〗探讨直丝弓正畸过程中龈沟液天冬氨酸转氨酶（aspartate transaminase，AST）、碱性磷酸酶（alkaline phosphatase，ALP）水平的变化对衡量牙周组织健康状况的参考价值。〖HTW〗方法〓〖HTK〗选择使用直丝弓矫治器的青少年患者44名,治疗前及安装矫治器1、3个月后采集龈沟液，采用生化分析仪检测分析龈沟液中AST、ALP的水平变化，并检查牙龈指数（GI）。〖HTW〗结果〓〖HTK〗矫治1个月时AST、 ALP水平比治疗前显著增高(P＜0.05)，3个月时AST、ALP酶水平趋于正常；1个月时GI比治疗前显著升高(P＜0.05)；3个月时GI比1个月时显著降低(P＜0.05)，但与治疗前比较差异无统计学意义(P＞0.05)。〖HTW〗结论〓〖HTK〗龈沟液AST、ALP可做为牙周组织炎性改变的重要衡量指标。

关键词: 天冬氨酸转氨酶, 碱性磷酸酶, 龈沟液, 直丝弓矫治器

Abstract:

Objective〓〖WTBZ〗To explore the effect of AST and ALP changes in gingival crevicular fluid for measurement of periodontal tissue health status during orthodontics therapy. 〖WTHZ〗Methods〓〖WTBZ〗44 teenager patients using a fixed appliance were enrolled in this study. Levels of AST and ALP in gingival crevicular fluid were determined by using biochemistry analysator before treatment， and one month and three months after treatment. 〖WTHZ〗Results〓〖WTBZ〗Levels of AST and ALP significantly increased one month after treatment but became normal three months after treatment. Gingival indexes of 1 month also significantly increased (P＜0.05), but they were not statistically different between the pre-treatment and the 3-month post-treatment period(P＞0.05). 〖WTHZ〗Conclusion〓〖WTBZ〗AST and ALP can be used to measure periodontal tissues.

Key words: straight wire appliance, Gingival crevicular fluid, Aspartate transaminase, Alkaline phosphatase

中图分类号:

R783.5

任旭升,王旭霞,张文娟,徐建光,张君 . 正畸治疗中龈沟液天冬氨酸转氨酶、碱性磷酸酶水平的变化[J]. 山东大学学报(医学版), 2008, 46(8): 804-806.

REN Xu-sheng,WANG Xu-xia,ZHANG Wen-juan,XU Jian-guang,ZHANG Jun

. Changes of the AST and ALP levels in gingival crevicular fluid during orthodontics treatment[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2008, 46(8): 804-806.

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