您的位置:山东大学 -> 科技期刊社 -> 《山东大学学报(医学版)》

山东大学学报(医学版)

• 论文 • 上一篇    下一篇

阻塞性睡眠呼吸暂停低通气综合征患者围手术期无创正压通气治疗的临床意义

涂春美1,刘洪英2,孙睿杰1,蔡晓岚1   

  1. 1. 山东大学齐鲁医院耳鼻咽喉-头颈外科, 济南 250012;2. 山东中医药大学第二附属医院耳鼻咽喉-头颈外科, 济南 250001
  • 收稿日期:2007-11-14 修回日期:1900-01-01 出版日期:2008-05-16 发布日期:2008-05-16
  • 通讯作者: 蔡晓岚

Perioperative continuous positive airway pressure treatment for obstructive sleep apnea hypopnea syndrome

TU Chun-mei1, LIU Hong-ying2, SUN Rui-jie1, CAI Xiao-lan1   

  1. 1. Department of Otorhinolaryngology & Head and Neck Surgery, Qilu Hospital of Shandong University, Jinan 250012, China;2. Department of Otorhinolaryngology & Head and Neck Surgery, Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, China
  • Received:2007-11-14 Revised:1900-01-01 Online:2008-05-16 Published:2008-05-16
  • Contact: CAI Xiao-lan

摘要: 目的研究无创正压通气(CPAP)治疗对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)围手术期的影响,探讨其对减少手术并发症的临床意义。方法对36例OSAHS患者行术前诊断性及CPAP治疗下的多道睡眠监测,分析CPAP治疗前后睡眠结构、呼吸、血氧饱和度及微觉醒等监测指标的变化。结果CPAP治疗后,各项指标较治疗前明显好转,患者睡眠结构趋于正常,1期浅睡眠减少,3+4期深睡眠及REM期睡眠明显增加;微觉醒、呼吸事件和血氧饱和度下降幅度明显减少;轻、中、重度OSAHS患者各项指标变化有一定差异。经CPAP治疗后张口呼吸减少,同时,通过术前咽腔局部药物雾化治疗,患者咽腔充血明显减轻,术中、术后出血量不多,无高血压危象等严重并发症出现。结论围手术期CPAP治疗可有效改善OSHAS患者的睡眠结构,并通过纠正呼吸紊乱和血氧饱和度下降,达到稳定血液动力学变化的目的,对提高手术和麻醉耐受性,降低围手术期风险具有重要的临床意义。

关键词: 围手术期, 持续正压通气, 外科, 阻塞性, 睡眠呼吸暂停

Abstract: To explore the effects of perioperative continuous positive airway pressure (CPAP) treatment for patients with obstructive sleep apnea hypopnea syndrome(OSAHS). MethodsThirtysix OSAHS patients were subjected to polysomonography(PSG) for preoperative diagnosis and for evaluation of the effect of the CPAP treatment. Two nights PSG results, including sleep architecture, breathing events, oxygen desaturation and arousal were compared. ResultsWith the CPAP treatment, stage 1 sleep was decreased, while stage 3+4 sleep and the REM sleep were significantly increased, also arousals, respiratory events and the degree of oxygen desaturation were significantly decreased. Changes of these parameters among mild, moderate and severe OSAHS patients were statistically different. Local edema and hyperemia in the pharyngeal cavity of OSAHS patients were relieved. No complications of hypertensive crisis happened. ConclusionPerioperative CPAP treatment could effectively decrease the breathing events and oxygen desaturation degree and steady hemodynamics, so as to make patients tolerate surgery and anaesthesia and reduce surgical crisis in the perioperation for OSAHS.

Key words: Sleep apnea, obstructive, Continuous positive airway pressure, Surgery, Perioperation

中图分类号: 

  • R766
[1] 祝林 胡三元 张光永 丁祥就. 前列腺素E2对阻塞性黄疸大鼠小肠粘膜形态的保护作用[J]. 山东大学学报(医学版), 2209, 47(6): 12-.
[2] 巩性军,吴树明,张供,李守先,庞昕焱. 无顶冠状静脉窦综合征的诊断和外科治疗[J]. 山东大学学报(医学版), 2209, 47(6): 129-.
[3] 赵继宗. 神经外科学是脑科学研究的一支主力军[J]. 山东大学学报 (医学版), 2020, 1(8): 1-4.
[4] 冯致余,杨彦亮,郭锐,徐惠惠,张健,郭凯,王广震,王辉. 肺动脉吊带合并气管狭窄的外科治疗[J]. 山东大学学报(医学版), 2017, 55(8): 48-51.
[5] 李岩,郭珺,王荣祺,刘永玲. 难治性癫痫相关Sturge-Weber综合征7例临床及病理分析[J]. 山东大学学报(医学版), 2017, 55(4): 91-95.
[6] 于晓琳,张军,杨柳,周林,崔亮亮,张济. 济南市慢性阻塞性肺部疾病患者在流感季呼吸系统疾病的罹患特征[J]. 山东大学学报(医学版), 2017, 55(3): 79-82.
[7] 王谋龙,陈永坤,邢德广,曲良锁,王成伟. 经颅多普勒超声早期预测动脉瘤夹闭术后迟发性脑缺血的临床分析[J]. 山东大学学报(医学版), 2017, 55(11): 38-41.
[8] 彭岳,冯振,谢厚耐,王晖,李猛,任万刚,刘通,彭忠民. 61例肺部多发病灶患者的外科治疗[J]. 山东大学学报(医学版), 2017, 55(11): 42-46.
[9] 潘青,吕志芳. 慢性阻塞性肺疾病新指南对临床患者分类的应用价值[J]. 山东大学学报(医学版), 2016, 54(3): 63-67.
[10] 卢中,申运华,严中亚,黄向阳,李春生,李华宝,杨冬妹. 经胸小切口封堵与经皮介入封堵术治疗房间隔缺损的比较[J]. 山东大学学报(医学版), 2016, 54(2): 49-52.
[11] 张红霞,徐永红,陈莉,龚辉成. 成人阻塞性睡眠呼吸暂停低通气综合征外周血TM、MPO的检测及意义[J]. 山东大学学报(医学版), 2016, 54(12): 67-71.
[12] 翟永华,徐淑军,马翔宇,李卫国,王芳,李新钢. 神经外科立体定向手术一次性手术铺巾的设计与应用体会[J]. 山东大学学报(医学版), 2016, 54(10): 90-91.
[13] 黄乃邦, 达鹏, 卢军, 吴昊. 不同下颌骨截骨方式在咽相关区域肿瘤手术中的应用[J]. 山东大学学报(医学版), 2015, 53(8): 79-82.
[14] 高南南, 陈栋, 于永慧, 张丽丽. 血清生物学标志物在新生儿坏死性小肠结肠炎手术评估中的价值[J]. 山东大学学报(医学版), 2015, 53(6): 73-76.
[15] 潘国政, 由法平, 王帅, 卜庆敖, 袁庆忠. 目标导向性液体治疗对老年患者腹部外科手术的影响[J]. 山东大学学报(医学版), 2015, 53(6): 82-85.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!