济南地区献血者中人疱疹病毒8型（HHV8）IgG抗体的检测及相关危险因素分析

山东大学学报(医学版)

济南地区献血者中人疱疹病毒8型（HHV8）IgG抗体的检测及相关危险因素分析

齐眉，赵蔚明，周亚滨，栾怡，卞继锋，王红，程轶?，刘娟，唐伟，于晗

山东大学医学院微生物学教研室，山东济南 250012

收稿日期:2005-06-16 修回日期:1900-01-01 出版日期:2006-04-24 发布日期:2006-04-24
通讯作者: 赵蔚明

Prevalance of human herpesvirus 8（HHV8）IgG and its associated risk factors in blood donors from Jinan region

QI Mei, ZHAO Weiming, ZHOU Yabin, LUAN Yi, BIAN Jifeng, WANG Hong,

Department of Microbiology, School of Medicine, Shandong University, Jinan 250012, Shandong, China

Received:2005-06-16 Revised:1900-01-01 Online:2006-04-24 Published:2006-04-24
Contact: ZHAO Weiming

摘要/Abstract

摘要： 目的：了解人疱疹病毒8型（HHV8）在济南地区不同献血者中的感染情况，并对其与年龄、性别、HBV、HCV、梅毒螺旋体的相关性进行统计学分析。方法：以HHV8 ORF K8.1合成多肽为抗原，采用ELISA方法检测献血者血清中相应IgG水平。结果：520份血清中抗HHV8 ORFK8.1抗体的总体检出率为5.962%（31/520），有随年龄增加而增高的趋势，但与性别、HBV、HCV、梅毒螺旋体的相关性无统计学意义。结论：济南地区献血者中有一定比率的HHV8感染。采取措施，防止HHV8经输血传播具有一定的现实意义。

Abstract: Objective: To estimate the seroprevalence of HHV8 infection and its correlation with hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis infection among blood donors in Shandong region. Method: Five hundred and twenty serum were tested for HHV8 IgG antibody with ELISA by using HHV8 ORF K8.1 peptides as antigen. Results: The mortality of positive HHV8 IgG antibody in blood donors from Jinan region was 5.962%（31/520）, and had a trend of increase with the blood donors′ increasing age, but it was not associated with exposure to HBV, HCV or syphilis. Conclusion: There is a certain rate of HHV8 infection in blood donors of Shandong. It is necessary to screen blood donors for HHV8.

Key words: Blood donors, Human herpesvirus 8, Immunoglobulin G

中图分类号:

R373.9

齐眉,赵蔚明,周亚滨,栾怡,卞继锋,王红,程轶?,刘娟,唐伟,于晗. 济南地区献血者中人疱疹病毒8型（HHV8）IgG抗体的检测及相关危险因素分析[J]. 山东大学学报(医学版), 2006, 44(4): 328-331.

QI Mei,ZHAO Weiming,ZHOU Yabin,LUAN Yi,BIAN Jifeng,WANG Hong,. Prevalance of human herpesvirus 8（HHV8）IgG and its associated risk factors in blood donors from Jinan region[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2006, 44(4): 328-331.

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