山东大学学报 (医学版) ›› 2025, Vol. 63 ›› Issue (7): 37-43.doi: 10.6040/j.issn.1671-7554.0.2024.0606
张蕾,潘叶,李家根,赵红
ZHANG Lei, PAN Ye, LI Jiagen, ZHAO Hong
摘要: 目的 评价Hughes改良瓣修复大面积下睑全层缺损的临床疗效。 方法 前瞻性研究,纳入大面积下睑全层缺损患者53例,按照手术方式分为对照组(n=28)和改良组(n=25)。对照组采用以Muller肌-结膜为蒂的上睑板-睑结膜瓣联合游离皮片修复下睑;改良组采用以上睑提肌腱膜-Muller肌-结膜为蒂的上睑全层瓣修复下睑。术中测量下睑缺损面积及重建时间。术后对患者进行随访,记录二期手术等待时间及并发症发生情况。 结果 两组下睑缺损面积差异无统计学意义(P>0.05),改良组下睑重建时间短于对照组[(62.1±7.4)min vs.(88.1±8.5)min,P<0.001]。术后随访(17.5±9.3)个月。改良组二期手术等待时间短于对照组[(11.2±3.0)d vs.(21.2±2.5)d,P<0.001]。改良组下睑退缩程度较对照组减轻(Z=-3.176,P=0.001),上睑退缩程度与对照组差异无统计学意义(t=0.351, P=0.727)。对照组2例(7.1%)出现坏死,两组均无伤口裂开、上睑下垂、睑内翻或睑外翻发生。 结论 Hughes改良瓣可有效地修复大面积下睑全层缺损,操作简单且二期切开等待时间短。
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