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山东大学学报 (医学版) ›› 2024, Vol. 62 ›› Issue (9): 30-35.doi: 10.6040/j.issn.1671-7554.0.2024.0375

• 主动脉疾病基础与临床研究进展专刊—研究进展 • 上一篇    

免疫性疾病相关主动脉病变诊疗进展

高健峰1,李方达1,吴亮霖1,曾嵘1,郑月宏1,2   

  1. 中国医学科学院北京协和医院 1.血管外科;2.疑难重症及罕见病国家重点实验室, 北京 100730
  • 发布日期:2024-10-10
  • 通讯作者: 郑月宏. E-mail: zhengyuehong_pumch@outlook.com
  • 基金资助:
    国家自然科学基金(82070492,82100519);创新工程重大协同创新项目(CIFMS2021-I2M-1-016);中央高水平医院临床科研专项(2022-PUMCH-B-100,2022-PUMCH-C-062)

Progress in diagnosis and treatment of immune disease related aortic lesions

GAO Jianfeng1, LI Fangda1, WU Lianglin1, ZENG Rong1, ZHENG Yuehong1,2   

  1. 1. Department of Vascular Surgery;
    2. State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China
  • Published:2024-10-10

摘要: 免疫性疾病相关主动脉病变一直是血管外科中充满挑战的病变,其主要表现为主动脉阻塞性或扩张性改变,从而引发脏器、肢体缺血或瘤体破裂致死风险。既往对于引发该类主动脉病变的免疫原发病诊断缺乏特异性,可能导致疾病综合管理方面的不足。本文从诊断和治疗两个方面分别诠释了常见免疫性疾病相关主动脉病变(大动脉炎、巨细胞动脉炎、白塞病)临床管理现状,并给出当前治疗不同类型主动脉病变的推荐方案,以期为临床工作和该领域未来发展提供参考。

关键词: 主动脉疾病, 免疫疾病, 开放手术, 腔内血管重建

Abstract: Immune-related aortic disease has always been a challenging lesion in vascular surgery, characterized by obstructive or dilated lesions in the aorta, leading to ischemia of organs and limbs, as well as the high mortality risk from aneurysm rupture. Previously, there was a lack of specificity in the diagnosis of the immune diseases that cause such aortic lesions, which may result in deficiencies in the comprehensive management of the disease. With the development of medical science, the management of this disease has been significantly improved, but its research progress still needs to be systematically summarized. This review aims to conclude the current status of the management for common immune-related aortic diseases(Takayasus aortitis, giant cell arteritis, Behcets arteritis)from diagnosis and therapy perspectives, and to provide recommendations for different types of aortic lesions, as well as to guide clinical work and future development in this field.

Key words: Aortic disease, Immunological disease, Open surgery, Endovascular revascularization

中图分类号: 

  • R654.3
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