南阳地区某医院急性心肌梗死患者院内用药10年变化趋势

doi:10.6040/j.issn.1671-7554.0.2016.1552

摘要/Abstract

摘要： 目的通过对2001~2011年南阳市中心医院急性心肌梗死(AMI)患者的院内用药分析,探讨10年间AMI患者院内用药的变化趋势,为AMI患者合理用药提供参考。方法随机选择该院2001、2006、2011年间AMI患者住院病历,提取详细临床信息,分析AMI患者阿司匹林、氯吡格雷、他汀、血管紧张素转换酶抑制剂(ACEI)/血管紧张素受体桔杭药(ARB)及β受体阻滞剂的使用情况及其变化趋势。结果共收集AMI病历234份,结果显示:2001~2011年,阿司匹林、氯吡格雷及他汀的应用率增加,差异具有统计学意义(阿司匹林:2001年80.0%,2006年86.0%,2011年94.8%, P=0.013;氯吡格雷2001年0.0%,2006年50.9%,2011年87.8%, P<0.001;他汀2001年34.0%,2006年81.8%,2011年95.6%, P<0.001),β受体阻滞剂和ACEI/ARB类药物应用率仍比较低,且10年间变化无统计学差异(β阻滞剂 2001年51.1%,2006年64.7%,2011年56.4%, P=0.401;ACEI类药物2001年62.5%,2006年72.2%,2011年60.9%, P=0.262)。结论过去10年间,南阳市中心医院AMI患者,阿司匹林、氯吡格雷及他汀使用率明显增加,β受体阻滞剂和ACEI/ARB类药物的使用仍与指南存在一定差距。

关键词: 治疗结果, 他汀, 抗血小板药物, ACEI/ARB类药物, β受体阻滞剂, 心肌梗死

Abstract: Objective To analyze the trend of drug use for inpatients with acute myocardial infarction(AMI)from 2001 to 2011, in order to provide reference for the rational use of drugs. Methods The medical records of inpatients in the year 2001, 2006 and 2011 were reviewed. The uses of aspirin, clopidogrel, stain, β blocker and angiotensin-converting-enzyme inhibitors(ACEI)/angiotensin receptor blockers(ARB)were assessed. Results A total of 234 cases were enrolled. There were significant increases in the use of aspirin(80.0%, 86.0%, 94.8%, P=0.013), clopidogrel(0%, 50.9%, 87.8%, P<0.001), and stain(34.0%, 81.8%, 95.6 %, P<0.001)in 2001, 2006 and 2011. The utilization rates of β blocker(51.1%, 64.7%, 56.4%, P=0.401)and ACEI/ARB(62.5%, 72.2%, 60.9%, P=0.262)were still relatively low, with no statistical difference in the past decade. Conclusion During the past decade, the uses of aspirin, clopidogrel and stain are significantly increased in Nanyang Central Hospital, but there is still gap between clinical practice and guideline in the uses of β blocker and ACEI/ARB.

Key words: Myocardial infraction, Treatment outcome, Stain, Antiplatelet, Angiotensin-converting-enzyme inhibitor/Angiotensin receptor blockers, β-blockers

中图分类号:

R542

高建步,杨守忠,李玉东,乔崇,张松雨. 南阳地区某医院急性心肌梗死患者院内用药10年变化趋势[J]. 山东大学学报（医学版）, 2017, 55(5): 66-69.

GAO Jianbu, YANG Shouzhong, LI Yudong, QIAO Chong, ZHANG Songyu. Trend survey of inpatient use of drugs for acute myocardial infarction during 10 years in a hospital of Nanyang City[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(5): 66-69.

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