山东大学学报（医学版） ›› 2015, Vol. 53 ›› Issue (1): 58-62.doi: 10.6040/j.issn.1671-7554.0.2014.551
王凤雪, 王倩, 李桂梅, 胡艳艳, 王增敏
WANG Fengxue, WANG Qian, LI Guimei, HU Yanyan, WANG Zengmin
摘要： 目的 探讨垂体强化核磁共振(MRI)对垂体柄阻断综合征(PSIS)的诊断价值并分析垂体MRI表现与垂体-靶腺功能损伤的相关性。方法 选取PSIS患儿64例(PSIS组),同时选取正常儿童及青少年60例(对照组)。根据垂体MRI表现将PSIS组分为部分性垂体柄阻断(pPSIS)组和完全性垂体柄阻断(cPSIS)组。检测相关激素水平,分析MRI表现与缺乏的激素种类数目及严重程度的相关性。结果 PSIS组垂体核磁共振表现与功能损伤呈正相关。比较垂体-靶腺激素,cPSIS组缺乏的激素种类数目及严重程度均显著高于pPSIS组(P<0.01)。PSIS组男性(24例,年龄均大于15岁)性激素水平显著低于对照组(P<0.05),cPSIS组男性睾酮水平显著低于pPSIS组(P<0.01),其余性激素水平无显著差异。结论 下丘脑-垂体区强化MRI可显示垂体柄的受损程度,可用于评估PSIS患儿垂体功能。
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