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山东大学学报(医学版) ›› 2017, Vol. 55 ›› Issue (3): 1-5.doi: 10.6040/j.issn.1671-7554.0.2016.1083

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“良性淋巴瘤”概念的提出及其存在的可能性

李文生   

  1. 陕西省人民医院 西安交通大学第三附属医院病理科, 陕西 西安 710068
  • 收稿日期:2016-08-30 出版日期:2017-03-10 发布日期:2017-03-10
  • 通讯作者: 李文生. E-mail:liwensheng263@hotmail.com E-mail:liwensheng263@hotmail.com
  • 基金资助:
    陕西省科技攻关课题(2010K12-02);陕西省卫生计生科研基金(2016D035)

Presentation of the concept of “benign lymphoma” and the discussion of the possibility of its existence

LI Wensheng   

  1. Department of Pathology, Shaanxi Provincial Peoples Hospital, Third Affiliated Hospital of the School of Medicine, Xian Jiaotong University, Xian 710068, Shaanxi, China
  • Received:2016-08-30 Online:2017-03-10 Published:2017-03-10

摘要: 淋巴瘤是一种来源于淋巴造血系统的肿瘤,按照以往的观点,淋巴瘤是一种单克隆增生的淋巴组织恶性肿瘤,没有“良性淋巴瘤”概念。近年来在淋巴瘤临床诊治实践中新发现一些生物学行为偏良性的单克隆增生淋巴组织病变,病变恶性潜能极其有限,几乎无进展,对传统淋巴瘤概念和诊断标准形成了一个挑战,也产生了一些疑问和困惑。基于此,作者在国内首次提出了“良性淋巴瘤”的观点并探讨其存在的可能性,期望以此引发专家们对淋巴瘤生物学本质问题的共同探讨和思考。

关键词: 淋巴瘤, 生物学本质, 克隆性, 良性淋巴瘤

Abstract: Lymphoma is a kind of tumor that comes from lymphatic hematopoietic. According to the previous points of views, lymphoma is a kind of malignant tumor which proliferates monoclonally. The concept of “benign lymphoma” does not exist at present. In the clinical practice of recent years, we have found that some monoclonal lymphoid tissue lesions show benign biological behavior and their malignant potential is extremely limited and almost does not develop, so it presents a challenge to the concept of lymphoma and its diagnostic standard. Based on this, the author proposes the concept of “benign lymphoma” here for the first time in China, and discusses the possibility of its existence, so as to 山 东 大 学 学 报 (医 学 版)55卷3期 -李文生.“良性淋巴瘤”概念的提出及其存在的可能性 \=-trigger the discussion on the biological essence of lymphoma.

Key words: Benign lymphoma, Clonality, Lymphoma, Biological essence

中图分类号: 

  • R733.4
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