毫米波雷达监测儿童阻塞性睡眠呼吸暂停综合征的诊断价值

doi:10.6040/j.issn.1671-7554.0.2025.1237

摘要/Abstract

摘要： 目的探讨毫米波雷达技术的非接触式便携睡眠呼吸监测设备(portable monitoring devices, PMD)在儿童阻塞性睡眠呼吸暂停(obstructive sleep apnoea, OSA)诊断中的应用价值。方法选取2023年7月至2024年7月在山东大学附属儿童医院就诊的4~15岁疑似OSA患儿101例作为研究对象,同步给予整夜多导睡眠(polysomnography, PSG)监测和清雷QS600PMD监测,以PSG为标准,对比分析两种设备在阻塞性呼吸暂停低通气指数(obstructive apnoea-hypopnea index, OAHI)、最低血氧饱和度(lowest pulse oxygen saturation, LSpO₂)等指标的差异及相关性,并按年龄、性别、合并症等进行亚组一致性分析,通过受试者工作特征曲线(receiver operating characteristic curve, ROC)评估清雷PMD的诊断效能,通过约登指数确定最佳诊断截断值,评估清雷PMD诊断儿童OSA的灵敏度与特异度。结果清雷PMD与PSG测得的OAHI差异无统计学意义(P>0.05),二者呈正相关(r_s=0.89, P<0.01)。组内相关系数(intraclass correlation coefficient, ICC)为0.85(P<0.01)。Bland-Altman一致性分析显示95.05%的数据点位于一致性界限内。各亚组一致性均达到良好及以上水平。清雷PMD与PSG测得的AHI、LSpO₂及平均血氧饱和度存在统计学差异(均P<0.01),但差异未达临床有意义阈值。ROC分析显示,清雷PMD诊断儿童OSA的曲线下面积(area under the curve, AUC)为0.91,最佳截断值(OAHI≥2.15次/h)时灵敏度为76.90%,特异度为100.00%。结论清雷PMD在儿童OSA诊断中与PSG具有高度一致性,核心指标OAHI测量可靠,兼具100%高特异度与非接触式监测优势,能提升患儿依从性,适用于基层医疗场景初筛,具有重要临床推广价值。

关键词: 儿童阻塞性睡眠呼吸暂停, 便携式睡眠呼吸监测, 多导睡眠监测, 诊断效能

Abstract: Objective To evaluate the application value of a sleep respiratory non-contact portable monitoring device(Qinglei PMD)based on millimeter-wave radar technology in the diagnosis of paediatric obstructive sleep apnoea(OSA). Methods A total of 101 children aged 4-15 years suspected of OSA from July 2023 to July 2024 were enrolled in the study. All participants underwent aseries of evaluations,including simultaneous overnight polysomnography(PSG, regardedas the gold standard)and Qinglei PMD monitoring. The differences and correlations of indicators including the obstructive apnoea-hypopnea index(OAHI)and the lowest pulse oxygen saturation(LSpO₂)between the two devices were analyzed. Subgroup consistency analysis was performed on the basis of age, gender, and comorbidities. The diagnostic efficacy of Qinglei PMD was assessed using the receiver operating characteristic curve(ROC). The optimal diagnostic cut-off value was determined via the Youden index, and the sensitivity and specificity of Qinglei PMD for diagnosing paediatric OSA were calculated accordingly. Results No significant statistical difference was observed in OAHI between Qinglei PMD and PSG(P>0.05), with a strong positive correlation(r_s=0.89, P<0.01)and an intraclass correlation coefficient(ICC)of 0.85(P<0.01). The Bland-Altman agreement analysis demonstrated that 95.05% of the data points fell within the limits of agreement, and consistency in all subgroups reached good or excellent levels. Statistical disparities were identified in AHI, LSpO₂, and mean oxygen saturation between Qinglei PMD and PSG(all P<0.01). However, these disparities did not attain clinically significant thresholds. ROC analysis revealed that the area under the curve(AUC)of Qinglei PMD for diagnosing paediatric OSA was 0.91. Utilizing the optimal cut-off value-of OAHI≥2.15 events/hour, the sensitivity was determined to be 76.90%, while the specificity was found to be 100.00%. Conclusion Qinglei PMD demonstrates a high degree of consistency with PSG in the diagnosis of paediatric OSA, with reliable measurement of the core indicator OAHI. The device exhibits both high specificity(100%)and non-contact monitoring advantages, which have the potential to enhance patient compliance and are well-suited for initial screening in primary healthcare settings. Consequently, it possesses significant clinical promotion value.

Key words: Paediatric obstructive sleep apnoea, Portable sleep monitoring, Polysomnography, Diagnostic performance

中图分类号:

R762

师晓丽,郭瑞祥,赵炎,边天帅,王晓华,牟鸿. 毫米波雷达监测儿童阻塞性睡眠呼吸暂停综合征的诊断价值[J]. 山东大学学报 (医学版), 2026, 64(9): 17-25.

SHI Xiaoli, GUO Ruixiang, ZHAO Yan, BIAN Tianshuai, WANG Xiaohua, MU Hong. Diagnostic value of millimeter-wave radar monitoring for paediatric obstructive sleep apnoea syndrome[J]. Journal of Shandong University (Health Sciences), 2026, 64(9): 17-25.

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