Journal of Shandong University (Health Sciences) ›› 2026, Vol. 64 ›› Issue (4): 38-43.doi: 10.6040/j.issn.1671-7554.0.2024.0757

• Clinical Medicine • Previous Articles    

Vestibular evoked myogenic potential in children with vestibular neuritis

LI Dongmei1, BIAN Tianshuai1, WANG Xiaohua1, ZHANG Jing2, ZHAO Yan1, SUN Sufen1, MU Hong1, XU Anting3   

  1. 1. Department of Otorhinolaryngology(Division 1), Childrens Hospital Affiliated to Shandong University, Jinan 250022, Shandong, China;
    2. Center for Hearing and Speech Rehabilitation, Childrens Hospital Affiliated to Shandong University, Jinan 250022, Shandong, China;
    3. Department of Otorhinolaryngology Head and Neck Surgery, The Second Hospital of Shandong University, Jinan 250033, Shandong, China
  • Published:2026-04-09

PDF (PC)

7

Abstract: Objective To analyze the vestibular evoked myogenic potential(VEMP)and explore the application value of VEMP examination in children with vestibular neuritis(VN). Methods A total of 59 children who visited the Otolaryngology Clinic of Childrens Hospital Affiliated to Shandong University from January 2023 to March 2024 were selected and divided into the control group(36 cases)and the VN group(23 cases)for retrospective analysis. All patients completed VEMPs examinations as required. Results The cervical vestibular-evoked myogenic potential(cVEMP)test results showed that the P1-N1 amplitude of both ears in the VN group was lower than that in the control group, with a statistically significant difference(P<0.05). There was no significant difference in the P1 and N1 latency between the two groups(P>0.05). The number of children in the VN group with a cVEMP amplitude asymmetry ratio(AR)value >35% was higher than that in the control group, with a statistically significant difference(P<0.05). The ocular vestibular-evoked myogenic potential(oVEMP)test results showed that the N1-P1 amplitude of the right ear in the VN group was lower than that in the control group, with a statistically significant difference(P<0.05). There was no significant difference in the N1-P1 amplitude of the left ear, and the P1 and N1 latency of both ears between the two groups(P>0.05). The number of children in the VN group with an oVEMP AR value >21% was higher than that in the control group, with a statistically significant difference(P<0.05). Conclusion The cVEMP and oVEMP waveforms in children with VN showed abnormal changes, suggesting that there were functional disorders in the saccule, utricle, and their conductive pathways. VEMP examination can be used as a diagnostic basis for VN and has important clinical significance.

Key words: Child, Vestibular neuritis, Vestibular evoked myogenic potential, Sacculus, Utriculus

CLC Number: 

  • R764
[1] Fancello V, Palma S, Monzani D, et al. Vertigo and dizziness in children: an update[J]. Children, 2021, 8(11): 1025. doi:10.3390/children8111025
[2] 刘冰, 李蓓, 张莉, 等. 儿童眩晕病因与年龄的相关性分析[J]. 临床耳鼻咽喉头颈外科杂志, 2019, 33(6): 508-511. LIU Bing, LI Bei, ZHANG Li, et al. Correlation analysis of vertigo etiology and age in children[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2019, 33(6): 508-511.
[3] Papathanasiou ES, Murofushi T, Akin FW, et al. International guidelines for the clinical application of cervical vestibular evoked myogenic potentials: an expert consensus report[J]. Clin Neurophysiol, 2014, 125(4): 658-666.
[4] 李斐, 鞠奕, 张甦琳, 等. 前庭神经炎诊治多学科专家共识[J]. 中华老年医学杂志, 2020(9): 985-994.
[5] Yu J, Zhou YJ, Xu XD, et al. Different findings of morphological changes and functional decline in the vestibule and the semicircular canal in ipsilateral delayed endolymphatic Hydrops[J]. Clin Neurophysiol, 2020, 131(7): 1487-1494.
[6] 李晓璐, 卜行宽, Kamran Barin, 等. 实用眼震电图和眼震视图检查[M]. 2版. 北京: 人民卫生出版社, 2015: 148-157.
[7] Schuknecht HF, Kitamura K. Vestibular neuritis[J]. Ann Otol Rhinol Laryngol, 1981, 90(1_Suppl): 1-19.
[8] Lin CM, Young YH. Identifying the affected branches of vestibular nerve in vestibular neuritis[J]. Acta Otolaryngol, 2011, 131(9): 921-928.
[9] 郭莉, 芦二永, 张超. 前庭诱发肌源性电位对前庭下神经炎的诊断价值[J]. 中国耳鼻咽喉头颈外科, 2017, 24(8): 402-404. GUO Li, LU Eryong, ZHANG Chao. Value of vestibular evoked myogenic potential on the diagnosis of inferior vestibular neuritis[J]. Chinese Archives of Otolaryngology-Head and Neck Surgery, 2017, 24(8): 402-404.
[10] 刘冰, 李蓓, 张莉, 等. 儿童前庭神经炎的前庭功能特点及预后分析[J]. 中华耳鼻咽喉头颈外科杂志, 2018, 53(12): 899-903. LIU Bing, LI Bei, ZHANG Li, et al. Vestibular function features and prognosis of vestibular neuritis in children[J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2018, 53(12): 899-903.
[11] Le TN, Westerberg BD, Lea J. Vestibular neuritis: recent advances in etiology, diagnostic evaluation, and treatment[J]. Adv Otorhinolaryngol, 2019, 82: 87-92. doi:10.1159/000490275
[12] Taborelli G, Melagrana A, DAgostino R, et al. Vestibular neuronitis in children: study of medium and long term follow-up[J]. Int J Pediatr Otorhinolaryngol, 2000, 54(2/3): 117-121.
[13] Arbusow V, Derfuss T, Held K, et al. Latency of herpes simplex virus type-1 in human geniculate and vestibular ganglia is associated with infiltration of CD8+T cells[J]. J Med Virol, 2010, 82(11): 1917-1920.
[14] Jeong J, Nam Y, Oh J, et al. Monthly and seasonal variations in vestibular neuritis[J]. Medicine, 2022, 101(26): e29787. doi:10.1097/MD.0000000000029787
[15] Greco A, Macri GF, Gallo A, et al. Is vestibular neuritis an immune related vestibular neuropathy inducing vertigo?[J]. J Immunol Res, 2014, 2014: 459048. doi:10.1155/2014/459048
[16] Shi XR. Physiopathology of the cochlear microcirculation[J]. Hear Res, 2011, 282(1/2): 10-24.
[17] Himmelein S, Lindemann A, Sinicina I, et al. Differential involvement during latent herpes simplex virus 1 infection of the superior and inferior divisions of the vesti-bular ganglia: implications for vestibular neuritis[J]. J Virol, 2017, 91(14): e00331-17. doi:10.1128/JVI.00331-17
[18] Lee SU, Park SH, Kim HJ, et al. Normal caloric res-ponses during acute phase of vestibular neuritis[J]. J Clin Neurol, 2016, 12(3): 301-307.
[19] 吕亚峰, 张道宫, 樊兆民, 等. 前庭神经炎患者前庭功能损伤的频率和部位特征分析[J]. 临床耳鼻咽喉头颈外科杂志, 2016, 30(8): 602-605. LYU Yafeng, ZHANG Daogong, FAN Zhaomin, et al. Frequency and position characteristics of the vestibular dysfunction in vestibular neuritis patients[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2016, 30(8): 602-605.
[20] Balatsouras DG, Koukoutsis G, Ganelis P, et al. Benign paroxysmal positional vertigo secondary to vestibular neuritis[J]. Eur Arch Otorhinolaryngol, 2014, 271(5): 919-924.
[1] WANG Qian, HU Xiaojing, WANG Aiqing, SUN Qiang, MENG Chunyan, LI Fanghua. Visual analysis of non-suicidal self-injury literature about children and adolescents with depressive disorder [J]. Journal of Shandong University (Health Sciences), 2026, 64(3): 93-107.
[2] LI Fanghua, LIU Na, LI Xiaoyu, XU Dianhua, WANG Qian. Research progress on medication adherence in children and adolescents with depressive disorder [J]. Journal of Shandong University (Health Sciences), 2026, 64(3): 24-34.
[3] WANG Shijian, ZHENG Doudou, AN Xuju, YANG Ying. Network analysis of childhood trauma and attachment in relation to adolescent somatic symptom disorder [J]. Journal of Shandong University (Health Sciences), 2026, 64(3): 45-54.
[4] KUANG Li, XU Heyan. From precision assessment to integrated intervention: innovations and future perspectives in the diagnostic and therapeutic paradigm for child and adolescent mental health disorders [J]. Journal of Shandong University (Health Sciences), 2026, 64(3): 10-16.
[5] SUN Jiali, WANG Liang, WANG Changfeng, ZHANG Jie, GUO Lei. Emotional and behavioral problems in children with Klippel-Trenaunay syndrome: characteristics and influencing factors [J]. Journal of Shandong University (Health Sciences), 2026, 64(3): 78-82.
[6] WANG Yueqi, SONG Dongyu, LI Yuli, XIE Hao, ZHANG Yuerong. Mediating role of childrens difficulties and prosocial behaviour in the relationship between family resilience and grandparenting stress [J]. Journal of Shandong University (Health Sciences), 2026, 64(1): 57-64.
[7] ZHANG Zheng, WANG Jianwei, YANG Yujuan, ZHANG Yu, SONG Xicheng. Immunoglobulin E changes and risk factors in asthma children between 2008 and 2019 [J]. Journal of Shandong University (Health Sciences), 2025, 63(7): 32-36.
[8] CAO Luofei, WANG Shanshan, WANG Jinrong, JIANG Heyun, MIAO Yu, MA Guangzeng. Analysis of the characteristics of bronchial dilation test in children with FeNO elevation during asthma exacerbation [J]. Journal of Shandong University (Health Sciences), 2025, 63(6): 38-44.
[9] LI Ling, YAN Yuhan, KONG Qingyu, WANG Minmin, ZHAO Haizhao, ZHAO Cuifen. Correlation between orthostatic intolerance symptom scores, catecholamine and emotional disorders in children with vasovagal syncope [J]. Journal of Shandong University (Health Sciences), 2025, 63(5): 71-78.
[10] CHEN Xujun, HE Guowei. Focus on further more use of arterial grafts in coronary artery bypass grafting in patients with coronary heart disease in China [J]. Journal of Shandong University (Health Sciences), 2025, 63(5): 1-5.
[11] MO Xuming, WANG Qingfeng. Application of coronary artery bypass grafting in pediatric cardiovascular disease [J]. Journal of Shandong University (Health Sciences), 2025, 63(5): 40-46.
[12] WANG Mengyuan, ZHANG Chunyan, YU Wenwen, KOU Linna, WANG Shifu. Composition and antifungal susceptibility surveillance of clinically isolated fungi from children and adults in Shandong Province from 2018 to 2021 [J]. Journal of Shandong University (Health Sciences), 2025, 63(4): 83-93.
[13] GONG Rong, CUI Naixue, CHEN Kaiyue, ZHAO Jia, SHAN Ruijie, ZHANG Xunqi. Application of exergaming on childhood cancer survivors [J]. Journal of Shandong University (Health Sciences), 2025, 63(4): 94-99.
[14] XIAO Changchun, YU Linling, YAN Derui, ZHU Yu. Effects of ozone on emergency room visits of respiratory diseases among children in Hefei City [J]. Journal of Shandong University (Health Sciences), 2025, 63(2): 95-103.
[15] SHI Wenxin, FAN Youjun, CHEN Yuan, LIU Haiyan, SUN Lifeng, GUO Lu. Two cases of pediatric celiac disease and literature review [J]. Journal of Shandong University (Health Sciences), 2025, 63(2): 51-57.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright 2018 © Editorial office of Journal of Shandong University (Health Sciences)
Supported by Beijing Magtech Co.Ltd