Journal of Shandong University (Health Sciences) ›› 2026, Vol. 64 ›› Issue (4): 31-37.doi: 10.6040/j.issn.1671-7554.0.2025.0553

• Clinical Medicine • Previous Articles    

Preliminary application of photoelectric detection devices in thyroid cancer surgery

LI Jingxiu1,2, LI Zhonghui2, LI Wentian1,2, WANG Yunan3, SONG Zehui3, ZHUANG Dayong2, HE Qingqing2, ZHOU Peng2   

  1. 1. Clinical and Basic Medical College, Shandong First Medical University(Shandong Academy of Medical Sciences), Jinan 250117, Shandong, China;
    2. Department of Thyroid and Breast Surgery, The 960th Hospital of the PLA Joint Logistics Support Force, Jinan 250031, Shandong, China;
    3. Department of General Surgery, The 961st Hospital of the PLA Joint Logistics Support Force, Qiqihaer161006, Heilongjiang, China
  • Published:2026-04-09

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Abstract: Objective To explore the safety and practicality of using near-infrared autofluorescence(NIRAF)and intraoperative neural monitoring(IONM)techniques in thyroid surgery for thyroid cancer, and to assess their impact on postoperative complications. Methods Twenty-one patients with thyroid cancer who underwent surgery at the 960th Hospital of the PLA Joint Logistics Support Force of China from January to March 2025 were enrolled. The intraoperative photoelectric detection device(equipped with NIRAF and IONM technologies)was used for thyroid surgery. The parathyroid glands were successively identified by empirical judgment and photodetection instrumentwith postoperative paraffin pathological examination as the gold standard. The function of the recurrent laryngeal nerve was monitored by the detection instrument, and postoperative complications were observed. Results A total of 101 suspicious parathyroid glands were identified using a combination of experience-based judgment and intraoperative photoelectric detection. The sensitivity, specificity, and accuracy of intraoperative photoelectric detection were 97.6%, 91.7%, and 94.1%, respectively; the corresponding indicators for experience-based judgment were 61.0%, 75.0%, and 69.3%, respectively. Per patient analysis revealed a statistically significant difference in diagnostic accuracy(Z=-3.91,P< 0.001). The intraoperative signal stability rate of IONM was 100.0%, and the median amplitude decreased by 3% from baseline postoperatively(IQR: -1.5% to 6.5%). No postoperative recurrent laryngeal nerve injury was observed, yielding a 95% confidence interval for nerve injury of 0% to 13.3% based on the exact binomial distribution. Conclusion The photoelectric detector, a novel device integrating NIRAF and IONM technologies, enables accurate identification and effective protection of parathyroid glands and nerves during thyroid surgery, thereby reducing postoperative complications.

Key words: Thyroid carcinoma, Near-infrared autofluorescence imaging, Intraoperative nerve monitoring, Parathyroid gland, Recurrent laryngeal nerve

CLC Number: 

  • R736.1
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