Journal of Shandong University (Health Sciences) ›› 2019, Vol. 57 ›› Issue (7): 1-5.doi: 10.6040/j.issn.1671-7554.0.2019.072

   

Advances of cellular immunotherapy for hematologic malignancies

HUANG Xiaojun   

  1. Peking University Peoples Hospital;
    Peking University Institute of Hematology;
    National Clinical Research Center for Hematologic Disease;
    Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing 100044, China
  • Published:2022-09-27

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Abstract: Immunotherapy has changed the therapeutic method and prognosis of malignant tumors. Hematopoietic stem cell transplantation is one of the earliest applied immunotherapy, which remains the essential treatment of many hematological malignancies. In recent years, new immunotherapy, such as CAR-T, PD-1 and NK cell therapy, has developed rapidly for the treatment of high-risk malignant hematological diseases, and has attracted attention from researchers all over the world. Cellular immunotherapy is suitable for patients with graft failure or contraindications, and is a less toxic alternative for relapsed/refractory patients. This paper reviews the advances of cellular immunotherapy for hematological malignancies.

Key words: Cellular immunotherapy, Hematologic malignancies, Review

CLC Number: 

  • R733.7
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