Journal of Shandong University (Health Sciences) ›› 2018, Vol. 56 ›› Issue (1): 50-56.doi: 10.6040/j.issn.1671-7554.0.2017.1115

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Precise sentinel lymph node biopsy in breast cancer guided by preoperative ultrasound combined with intraoperative lymphatic drainage

CHEN Sisi, LI Xiaoyan, JIANG Liyu, KONG Xiaoli, MA Tingting, YANG Qifeng   

  1. Department of Breast Surgery, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Published:2022-09-27

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Abstract: Objective Sentinel lymph node biopsy(SLNB)was monitored during the complete surgical procedures to achieve accurate treatment and to determine its clinical value. Methods Axillary lymph nodes were assessed by ultrasound before operation. The lymph nodes near breast which were abnormally enlarged were marked. Intraoperatively, the lymph vessels and nodes were stained with both methylene blue and indocyanine green(ICG). After the true sentinel lymph nodes(trSLNs), para-SLNs(paSLNs)and post-SLNs(poSLNs)were accurately distinguished, the trSLNs were resected for biopsy. Results The evaluation of 126 cases of breast cancer revealed that the coincidence rate of preoperative ultrasound diagnosis was 78.8%. The SLNB specificity, sensitivity, and false negative rate(FNR)were 100%, 88.1% and 11.9%, respectively. The false negative of multifocal tumor was statistically significant(P=0.009), while preoperative assessment of lymph node status and paSLN metastasis were not statistically significant. Conclusion Preoperative ultrasound localization combined with intraoperative drainage guided SLNB can cause few trauma and low false negative rate. Multifocal tumor is a risk factor of false negative.

Key words: Sentinel lymph node, Lymphatic drainage, Ultrasound, Biopsy, Breast cancer

CLC Number: 

  • R615
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