Abstract: To explore the characteristics of tetramine poisoning within 3 years old, the therapeutic effects and advertent problems of hemoperfusion therapy. Methods: The serum tetramine composition was determined by gas chromatograph method． The clinical data of 42 infants and toddlers were analyzed. They were divided into mild, moderate and severe groups. The serum levels of tetramine and myocardial enzymes were compared with its severity. The effects and adverse reactions of hemoperfusion therapy were summarized. Results: Tuentysix cases were misdiagnosed, 22 cases were in status epilepticus and coma. The levels of myocardial enzymes in the severe group were obviously higher than those of moderate group (P＜0.05). The clinical state was worse when the serum tetramine concentration was higher than or equal to 80 ng/ml. The prognosis in the hemoperfusion group was obviously better than the nonehemoperfusion group(P＜0.05). Severe complications were found in 5 cases. Conclusion: Tetramine poisoning in infants and toddlers is easily misdiagnosed, especially in status epilepticus and coma. The severity is positively associated with the increase of myocardial enzymes and tetramine concentration. Hemoperfusion is effective, however, it may have severe consequences.

Key words: Tetramine, Tetramine, Poisoning, Poisoning, Hemoperfusion, Hemoperfusion, Myocardial enzyme, Myocardial enzyme, Infants , Infants