Abstract: Objective To analyze the trend of drug use for inpatients with acute myocardial infarction(AMI)from 2001 to 2011, in order to provide reference for the rational use of drugs. Methods The medical records of inpatients in the year 2001, 2006 and 2011 were reviewed. The uses of aspirin, clopidogrel, stain, β blocker and angiotensin-converting-enzyme inhibitors(ACEI)/angiotensin receptor blockers(ARB)were assessed. Results A total of 234 cases were enrolled. There were significant increases in the use of aspirin(80.0%, 86.0%, 94.8%, P=0.013), clopidogrel(0%, 50.9%, 87.8%, P<0.001), and stain(34.0%, 81.8%, 95.6 %, P<0.001)in 2001, 2006 and 2011. The utilization rates of β blocker(51.1%, 64.7%, 56.4%, P=0.401)and ACEI/ARB(62.5%, 72.2%, 60.9%, P=0.262)were still relatively low, with no statistical difference in the past decade. Conclusion During the past decade, the uses of aspirin, clopidogrel and stain are significantly increased in Nanyang Central Hospital, but there is still gap between clinical practice and guideline in the uses of β blocker and ACEI/ARB.

Key words: Myocardial infraction, Treatment outcome, Stain, Antiplatelet, Angiotensin-converting-enzyme inhibitor/Angiotensin receptor blockers, β-blockers