JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2015, Vol. 53 ›› Issue (1): 67-72.doi: 10.6040/j.issn.1671-7554.0.2014.078

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Comparison of treatment outcomes after two different surgical approaches for operable middle thoracic esophageal squamous cell carcinoma

MA Honghai, DU Jiajun   

  1. Department of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong, China
  • Received:2014-02-19 Revised:2014-12-17 Published:2015-01-10

Abstract: Objective To compare the efficacy of two different surgical routes for operable esophageal squamous cell carcinoma (ESCC). Methods A total of 107 patients with middle thoracic ESCC were enrolled and divided into two groups: left transthoracic approach group and Ivor-lewis approach group. Cox regression analysis and Kaplan-Meier curves were used to explore the difference of survival in the two groups. Postoperative complications, information on lymph node dissection and other clinical factors were compared using non-parametric test and Chi-Square test. Results There were no significant differences between the two groups in the patients' characteristics, overall survival (P=0.315), recurrence-free survival (P=0.246), chest drainage volume (P=0.241), number of resected (P=0.065) and positive lymph nodes (P=0.188). However, blood loss (P=0.007) and operation time (P=0.042) were significantly less or shorter in left transthoracic approach group. T status (P=0.001), N status (P=0.007), as well as metastatic lymph node ratio (MLR, P=0.040), were shown as independent prognostic risk factors by COX regression analysis. Conclusion Both Ivor-Lewis approach and left transthoracic approach are optional surgical routes for operable middle thoracic ESCC.

Key words: Lymph node excision, Esophageal squamous cell carcinoma, Esophagectomy

CLC Number: 

  • R655.4
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