Abstract:

Objective   To investigate the clinical efficacy of 32P applicator combined  with needleless skin instrument for treating chest keloid． Methods   Of all the 180 chest keloid patients, 60 with lesion thickness ≤0.2cm were randomly divided into three groups： 20 received compound betamethasone injection therapy, 20 received 32P applicator therapy, others were treated with 32P applicator combined with needleless skin instrument. 120 ones with lesion thickness >0.2cm were randomly divided into four groups: 30 received compound betamethasone injection therapy, 30 received 32P applicator therapy, 30 received operation combined with 32P applicator therapy， others were treated with operation combined with 32P applicator and needleless skin instrument. Results   ① The cure rate and effective rate in the compound betamethasone injection group were 35.0% and 55.0%, which were significantly lower than those(75.0%, 85.0%)in the simple 32P application group and (80.0%, 90.0%)in the 32P applicator combined with needleless skin instrument group(P<0.05); ② The cure rate and effective rate in the compound betamethasone injection group were 3.3% and 23.3%, which were significantly lower than those in the other groups(P<0.05); The cure rate and effective rate in the simple 32P application group were 20.0% and 53.3%, which were significantly lower than those(86.7%, 96.7%) in the operation combined with 32P applicator and needleless skin instrument group and in the operation combined with 32P applicator group(P<0.05); The cure rate in the operation combined with 32P applicator and needleless skin instrument group was significantly higher than that in the operation combined with 32P applicator group(P<0.05). Conclusion   For patients with lesion thickness ≤0.2cm， 32P applicator therapy only is enough． Otherwise， patients are suggested to use operation combined with 32P applicator and needleless skin instrument therapy.

Key words: Needleless skin instrument ; 32P applicator; Keloid ； Compound betamethasone; Tension