Abstract:

Objective   To investigate the role of hemorrhagic fever with renal syndrome(HFRS)critical score in predicting the prognosis for patients with HFRS. Methods   A total of 120 patients diagnosed as HFRS were divided into the survival group (90 cases) and the death group (30 cases) according to the prognosis. HFRS critical score consisted of SIRS state, extravasation, plasma colloid osmotic pressure, platelet count and urinary protein. The results of HFRS critical score were compared with the SOFA score and the  SAPS Ⅱ score. Results   All of the five parameters of HFRS critical scores in the death group were significantly higher than those in the survival group. The score of HFRS critical score, SOFA scores and SAPS Ⅱ score in the death group were significantly higher than those in the survival group(P<0.01). The area under the curve (AUC) of SOFA score, SAPS Ⅱ scores and HFRS critical score was 0.704, 0.731 and 0.804 respectively. The Youden index of the HFRS critical scores was the highest (P<0.01) among all three scores . If HFRS critical score 10 was used as the cut off value, the specificity and the sensitivity for predicting the death risk for the patient in admit was respectively 77.4% and 78.8%. Conclusion   HFRS critical score, SOFA score, and SAPS Ⅱ score can all effectively predict prognosis for HFRS patients, among which the HFRS critical scores are more easy and convenient , and have the best predictive value.

Key words: Hemorrhagic fever with renal syndrome; Critical score; SOFA score; SAPS Ⅱ score; Receiver operating characteristic curve