JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2016, Vol. 54 ›› Issue (2): 49-52.doi: 10.6040/j.issn.1671-7554.0.2015.223

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Treatment of atrial septal defect: minimally invasive occlusion procedure vs percutaneous interventional occlusion

LU Zhong1, SHEN Yunhua1, YAN Zhongya1, HUANG Xiangyang2, LI Chunsheng1, LI Huabao1, YANG Dongmei2   

  1. 1. Department of Cardiac Surgery;
    2. Echocardiogram Room, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, Anhui, China
  • Received:2015-03-01 Online:2016-02-10 Published:2016-02-10

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Abstract: Objective To compare the clinical efficacy, advantages and disadvantages between minimally invasive occlusion procedure and percutaneous interventional occlusion for treating patients with atrial septal defect(ASD). Methods The clinical data of 146 ASD patients treated during Jan. 2004 and Aug. 2014 were retrospectively analyzed. The patients were divided into 2 groups: group A(n=43)were treated with minimally invasive occlusion procedure under the guidance of transesophageal echocardiography(TEE); group B(n=103)received percutaneous interventional occlusion guided by TEE and digital subtraction angiography(DSA). Clinical data before and after the surgery were collected; efficacy and cost of both approaches were compared. Results Age, gender, body weight and diameter of ASD were similar between the two groups(all P>0.05). Operation time, postoperative hospital stay and mean total cost were significantly lower in group B than in group A(all P<0.05). All cases in group A were successfully occluded with satisfactory results. The 2 unsuccessful patients in group B switched to emergency surgical operation. No patients in both groups needed blood transfusion and no death occurred. One month after operation, transthoracic echocardiography(TTE)derived diameters of left atrial and left ventricular were smaller than those preoperative(both P<0.05). Incidence of residual shunt, and left ventricular ejection fraction were similar before and 1 month 山 东 大 学 学 报 (医 学 版)54卷2期 -卢中,等.经胸小切口封堵与经皮介入封堵术治疗房间隔缺损的比较 \=-after operation(both P>0.05). Conclusion The two approaches are both minimally invasive operation for treating ASD, which can be performed safely and effectively. Minimally invasive occlusion procedure does not need X-ray, and has higher success rate and wider indications than percutaneous interventional occlusion. Percutaneous interventional occlusion shortens the operation time and hospitalization, has lower medical cost, and provides better cosmetic results.

Key words: Minimally invasive, Percutaneous interventional occlusion, Atrial septal defect, Surgical procedures

CLC Number: 

  • R654.2
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