JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2013, Vol. 51 ›› Issue (12): 61-66.

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Effects of type of PVTT on long-term outcomes of  surgical treatment for hepatocellular carcinoma

MENG Hai-peng, NIU Wei-bo, WU Xiao-peng, GUO Sen, LIU Yi, CHEN Yu-xin   

  1. Department of  hepatobiliary surgery, Qilu Hospital of Shandong University, Jinan 250012, China
  • Received:2013-03-02 Online:2013-12-10 Published:2013-12-10

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Abstract:

Objective   To evaluate effects of location and extent of PVTT on long-term outcomes of surgical treatment for hepatocellular carcinoma(HCC).  MethodsA retrospective study was carried out on patients who underwent partial hepatectomy with or without portal thrombectomy for HCC with PVTT in Qilu Hospital of Shandong University from January 2010 to December 2012. The patients′ clinical characteristics, recurrence and survival were analyzed. Results   A total of 203 patients with HCC and portal vein tumor thrombus(PVTT) who underwent partial hepatectomy were studied. The complication rate and hospital mortality rate were respective 30.0% and 0.5%,  and median follow-up was 6.5 months. The 1- and 3-year overall survival rates were 33.5% and 12.8%, respectively.  The 1- and 3-year disease-free survival rates were 10.8% and 3.0%, respectively. Patients with VP1,VP2 and VP3 showed significantly better survival than those with VP4.  ConclusionLiver resection is justified in selected patients with VP1,VP2 and VP3. However, surgical resection for PVTT involving the main trunk (VP4) is still controversial.

Key words: Hepatocellular carcinoma; Portal vein tumor thrombus; Portal vein; Surgical treatment

CLC Number: 

  • R735.7
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