Abstract:

Objective   To analyze the influence and forecast value of stress hyperglycemia on the recovery of daily living activity in stroke patient. Methods   The clinical data of 459 nondiabetics stroke patients was retrospectively analyzed. The patients were devide into three groups according to the fasting plasma glucose level. They were the euglycemia group(FBG<6.1mmol/L), the mild stress hyperglycemia group (6.1mmol/L≤FBG<7.0mmol/L) and the severe stress hyperglycemia group (FBG≥7.0mmol/L). The statistical data included age, diseases history, blood biochemistry test, blood coagulability and hemostatic function test, CT, MRI and Activities of Daily Living Assessment (ADL). PASW 18.0 was used for the statistical analysis and statistical significance was set at P<0.05. Results   The risk of stress hyperglycemia was higher in senile patients (>65 years old) with atrial fibrillation, hypertension or hypertriglyceridemia. Cerebral hemispheric infarction was connected with stress hyperglycemia. At the same time,fasting plasma glucose(FBG). Prothrombin Time % (PT%). fibrinogen (Fib).  D-dimer (D-Di) and blood urea nitrogen (BUN) were closely related to the ADL score. The ADL score of the mild stress hyperglycemia group and the severe stress hyperglycemia group was lower than that of the euglycemia group, while it was also lower in the severe stress hyperglycemia group than in the mild stress hyperglycemia group. Stress hyperglycemia was positively correlated with the high risk of activity disorder in stroke patients(rs=-0.2643，  P<0.0001). Conclusions   Stress hyperglycemia in patients with cerebral infarction increases the risk of daily living activity disorder. 

Key words:  Stroke; Stress hyperglycemia; ADL scale; Activity disorder; Forecast value