JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2011, Vol. 49 ›› Issue (7): 113-116.

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Cause of morning surge hypertension

ZHU Yan-li1, WANG Xiu-li2, ZHU Xue-mei1,  ZHUO Jing-ming1,  LI Wen-hua1   

  1. 1. Department of Geriatric Cardiac Diseases, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China; 2. East Suburban Hospital of Zaozhuang Mining Group, Zaozhuang 277110, Shandong,  China
  • Received:2011-01-24 Online:2011-07-10 Published:2011-07-10

Abstract:

Objective      To investigate risk factors for morning surge in hypertension. Methods        201 cases were divided into the morning surge group and the non-morning group. The levels of plasma rennin activity(PRA), angiotensin II(AngⅡ), aldosterone(ALD), growth hormone(GH) and cortisol(COR) were detected. The correlation between sleeptrough morning surge variability and levels of AngⅡ, ALD, GH and COR were analyzed. Results        AngⅡ and ALD levels in the morning surge group are higher than those in the non-morning group(P<0.05), GH and COR levels were also higher(P<0.01). Sleep-trough morning surge had positive correlations with levels of AngⅡ(r=0.42, P<0.01 ), ALD(r=0.28, P<0.05 ), GH(r=0.45, P<0.001 ) and COR(r=0.32, P<0.01). Conclusion      Morning surge hypertension is closely related to activation of the renin-angiotension system and levels of GH and COR.

Key words: Hypertension; Morning surge; AngiotensinⅡ; Somatropin; Hydrocotisone

CLC Number: 

  • R544.1
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