Abstract:

Objective     To summarize the experience of treating non-muscle invasive bladder cancer， using transurethral holmium laser resection of the bladder followed by intravesical instillation of Pirarubicin. Methods     From August 2007 to August 2009, 52 patients with non-muscle invasive bladder cancer were treated with the transurethral holmium laser resection of the bladder cancer followed by intravesical chemotherapy of Pirarubicin.  Results      The tumors  were completely resected. The operating time were 15 to 60 minutes, 30 minutes in average.  No serious complications, such as bladder perforation during the procedure and bleeding in the perioperative period occurred. All cases were followed for 12 to 24 months after operation, and 5 of the patients ( 9.6%) had recurrent bladder cancer during follow-ups and were retreated with the same method. Conclusion      Combination of holmium laser resection of bladder with intravesical chemotherapy of Pirarubicin is an effective and safe therapy, with accurate resection, less bleeding and injuries, earlier recovery and lower recurrence. 

Key words: Bladder cancer; Holmium laser; Bladder instillation