JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2010, Vol. 48 ›› Issue (12): 94-.

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Estimation of dialysis dose (Kt／V Urea) by online clearance monitoring in  hemodialysis patients with end stage of renal disease

SUI Zhun, WANG Mei   

  1. Department of Nephrology,  The People′s Hospital of Beijing University,  Beijing 100044， China
  • Received:2010-10-20 Published:2010-12-16

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Abstract:

Objective    To investigate the relationship between dialysis dose measured by online clearance monitoring (OCM) and Kt／V Urea from pre-and post-dialysis blood-urea samples, and set up a prediction rule to estimate spKt/V by OCM. Methods    OCM and Kt／V Urea data from 74 hemodialysis patients were measured. The relationship between OCM and Kt／V Urea was analyzed by correlation assay. Clinical parameters were put into the linear regression formula, based on which the prediction rule was calculated to estimate Kt／V Urea by OCM.  Results     Dialysis dose measured by OCM was lower than Kt／V Urea, and they had close relationship（r=0.690，P<0.001）. Based on clinical parameters,  Kt／V Urea could be calculated by OCM. Conclusion      There is close relationship between OCM and Kt／V Urea.  And based on clinical characters, Kt／V Urea could be calculated by OCM.

Key words: Hemodialysis; Adequacy; Online clearance monitoring

CLC Number: 

  • R692.5
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