JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2009, Vol. 47 ›› Issue (9): 36-39.

• Articles • Previous Articles     Next Articles

Changes of TNFα in dental pulp by using distraction 
osteogenesis on orthodontic rapid tooth movement

GUO Xinxing1,　ZHANG Yong1, CHEN Jing2，　YE Jing1     

  1. 1. Department  of  Orthodontics, Jinan Stomatological Hospital, Jina n 250001, China;
    2. Stomatological Hospital of Shandong University, Jinan 250012, China
  • Received:2008-10-09 Published:2009-09-16

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Abstract:

To observe the changes of TNFα in  dental pulp by using distraction osteogenesis on orthodontic rapid tooth movement. Methods Quantity of TNFαin different stages was detected by ELISA. ResultsThe quantity of TNFαgreatly increased right after four weeks′ distraction force, while it significantly decreased during the first and second week after stopping distraction osteogenesis, and the quantity of TNFαchanged little during day 14 to 28 after stopping distraction osteogenesis, but the TNFαlevel during day 14 to 28 was lower than that of the control group. ConclusionsThe quantity of TNFα could return to the normal level in two weeks after 4 weeks′ distraction force applied to the orthodontic tooth. Day 7 to 14 is the period that the dental pulp  becomes healthy. Orthodontic rapid tooth movement has a slight effect on the dental pulps activity.

Key words: Dentoalveolar distraction osteogenesis; Dental pulp ; Tumor necrosis factor alpha; Rapid tooth movement

CLC Number: 

  • R783.5
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