Journal of Shandong University (Health Sciences) ›› 2022, Vol. 60 ›› Issue (3): 83-88.doi: 10.6040/j.issn.1671-7554.0.2021.0996

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Application value of three-dimensional visualization combined with indocyanine green fluorescence technique in laparoscopic hepatectomy in the treatment of 51 patients with primary liver cancer

LI Bo, LIU Jingfang, BAO Jinpeng, LI Xiangze, QIN Guangyang, TIAN Hu   

  1. Department of General Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine Shandong University, Jinan 250014, Shandong, China
  • Published:2022-03-09

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Abstract: Objective To explore the advantages of three-dimensional visualization combined with indocyanine green(ICG)fluorescence imaging in laparoscopic liver resection of primary liver cancer(PLC). Methods A retrospective case-control study was conducted to involve 105 PCL patients treated during Jan. 2019 and Jan. 2021, including 51 cases treated with laparoscopic hepatectomy combined with ICG fluorescence imaging(observation group)and 54 cases treated with conventional laparoscopic hepatectomy resection of PLC(control group). The baseline data, operation time, hilar occlusion time, blood transfusion, hospital stay, postoperative pathology, complications and follow-up data at 1st, 3rd and 6th months after operation were collected. The curative effect, incidence of complications and short-term postoperative recurrence were compared between the two groups. Results The operation time ［225(135)vs 282.5(118)min, Z=-2.687, P=0.007］ and intraoperative portal occlusion time ［(35.9±8.5)vs(240.7±6.8)min, t=-3.183, P=0.002］ were shorter in the observation group than in the control group. The intraoperative bleeding volume ［300(200)vs 363(141)mL, Z=-2.621, P=0.009］, incidence of complications ［5(4.8%)vs 14(13.3%), χ2=-4.600, P=0.032］, and level of glutamic pyruvic transaminase(ALT)on day 1 ［332.1(131.7)vs 386.2(100.0), Z=-2.379, P=0.017］, day 3 ［(227.1±76.1)vs(274.8±74.0), t=-3.257, P=0.002］ and day 5 ［(114.4±51.7)vs(151.1±61.0), t=-3.254, P=0.001］ were lower in the observation group than in the control group. Conclusion Compared to the conventional laparoscopic liver resection, three-dimensional visualization combined with ICG fluorescence imaging technique has advantages of shorter operation time and intraoperative hepatic hilar occlusion time, less operative bleeding and liver function damage, and fewer postoperative complications, which best embodies the concept of precise hepatectomy.

Key words: Three-dimensional visualization, Indocyanine green, Primary liver cancer, Laparoscopic hepatectomy

CLC Number: 

  • R735.7
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