Journal of Shandong University (Health Sciences) ›› 2020, Vol. 58 ›› Issue (5): 1-5.doi: 10.6040/j.issn.1671-7554.0.2020.352

   

Concept and prevention of prolonged postoperative ileus

JIANG Zhiwei, WANG Gang   

  1. Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, Jiangsu, China
  • Published:2022-09-27

Abstract: Postoperative ileus, which develops after abdominal surgical procedures, is an iatrogenic disorder characterized by a transient inhibition of gastrointestinal motility. Its mechanism involves surgical trauma, anesthetics, sympathetic nervous system hyperreaction, intestinal inflammatory response, and so on. From the pathophysiological perspective, POI can be classified into early neurogenic stage and later inflammatory stage; from the clinical perspective, it can be classified into physiological POI and prolonged POI(PPOI). The normalized definition of PPOI is helpful to collect the accurate incidence, analyze its risk factors and propose preventive and therapeutic measures. The concept of accelerated recovery after surgery(ERAS)and minimally invasive surgery have significantly reduced the incidence of PPOI. Although achievements have been made in the prevention and treatment, PPOI remains a challenging clinical problem.

Key words: Postoperative ileus, Prolonged postoperative ileus, Pathophysiology, Enhanced recovery after surgery

CLC Number: 

  • R619
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