Journal of Shandong University (Health Sciences) ›› 2020, Vol. 58 ›› Issue (1): 81-86.doi: 10.6040/j.issn.1671-7554.0.2019.764

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Clinical features of 9 cases of cryptogenic organizing pneumonia and literature review

WANG Huasheng1, OU Renjie2, WANG Mo3, BAI Longzhen2,LI Yingjie2, SUN Chao2, WANG Yongmei4   

  1. 1. Department of Thoracic Surgery, The Second Hospital of Shandong University, Jinan 250033, Shandong, China;
    2. Department of Thoracic Surgery, The Shandong Linglong Yingcheng Hospital, Zhaoyuan 265400, Shandong, China;
    3. Department of Vascular Surgery, Shandong Provincial Hospital Affilited to Shandong University, Jinan 250021, Shandong, China;
    4. Department of Cardiology, The Second Hospital of Shandong University, Jinan 250033, Shandong, China
  • Published:2022-09-27

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Abstract: Objective To summarize cryptogenic orgenizing pneumonia(COP)s clinical and radiographic features. Methods Nine cases COP were reviewed. Their clinical presentation, radiographic and pathology features were analyzed. Results Cough(66.7%)and chest tightness(55.6%)were the most common symptoms in those patients. CRP and ESR were increased distinctly. Chest CT was characterized by bilateral or unilateral patchy or dffuse con-solidation(55.6%), and migration was its characteristic radiographic feature. In pathological staining, the alveoli and bronchioles were filled with loose fibroblast connective tissue thrombus, which was round or dumbbell-shaped. COP was sen-sitive to corticosteroid therapy, and had a good outcome. Conclusion COP has its own radiographic characteristics and sensitive to corticosteroid treatment. Attention should be paid to the disease to avoid misdiagnosis and mistreatment.

Key words: Cryptogenic organizing pneumonia, Clinical features, Radiographic characteristics, Corticosteroid

CLC Number: 

  • R563
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