Abstract: Objective To explore the hysteroscopic features of endometrial polyps and the diagnostic value. Methods The study collected the clinical information of 567 patients during Aug. 2012 and Jan. 2019 who were diagnosed with ultrasound and hysteroscopy as endometrial polyps, and then received biopsy or resection of polyps under hysteroscopy. According to the pathological results, the patients were divided into two groups, 514 cases in the benign group and 53 caes in the malignant and pre-malignant group. The characteristics of endometrial polyps under hysteroscopy, the patients’ age, pregnancy history and ultrasound results were analyzed. Results The malignant and pre-malignant group were more likely to be menopausal and have symptoms of abnormal uterine bleeding than the benign group(47.16% vs 21.79%, P<0.001; 92.45% vs 70.82%, P<0.001). Surface vascular hyperplasia was the risk factor of malignant transformation of polyps, whose incidence was higher in the malignant and pre-malignant group than in the benign group(60.37% vs 9.33%, P<0.001). Multivariate binary Logistic regression analysis showed that surface vascular hyperplasia(OR=14.73, 95%CI:7.88-27.53), abnormal uterine bleeding(OR=5.05, 95%CI:1.79-14.24)and menopause(OR=3.21, 95%CI:1.80-5.72)were risk factors of polyp malignant transformation, and surface vascular hyperplasia had the highest risk. Conclusion Due attention should be paid to menopause, abnormal uterine bleeding and surface vascular hyperplasia as they are risk factors of malignant transformation of endometrial polyps.

Key words: Endometrial polyps, Endometrial malignancies, Hysteroscopy, Abnormal uterine bleeding