Journal of Shandong University (Health Sciences) ›› 2020, Vol. 58 ›› Issue (11): 81-84.doi: 10.6040/j.issn.1671-7554.0.2019.1435

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Analysis of the bronchodilator test of 122 patients with asthma

LI Yan, NIU Rui, WANG Chaochao   

  1. Department of Respiratory, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, Shandong, China
  • Published:2020-11-04

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Abstract: Objective To analyze the results and characteristics of pulmonary function test and bronchodilator test in patients with asthma, and to explore the value of pulmonary function test in diagnosis and curative effect of asthma. Methods Pulmonary function results of 122 patients with asthma in 2018 were collected. According to FEV1/FVC%, the cases were divided into normal group(n=30)and airflow restricted group(n=92). Airflow restricted group was further divided into mild group(n=63), moderately severe group(n=16)and severe group(n=13)based on FEV1. Then the data of different groups were analyzed. Results The positive rates of bronchodilator test were 16.7%, 58.7%, 81.3%, and 100.0% in normal group, mild group, moderately severe group, and severe group, respectively, with a statistical difference between different groups(χ2=35.8, P=0.001). There was no significant difference of improvement quantity and improvement rate between FEV1 and FVC in normal group(P=0.39, P=0.14). FEV1/FVC% values before and after bronchodilator test in moderately severe group and severe group were lower than that in mild group(before the test: χ2=52.16, P<0.001; after the test: χ2=49.49, P<0.001). FEV1/FVC% value was increased after bronchodilator test in all airflow restricted groups(all P<0.05). Only 9.8% of patients were released from air restriction after bronchodilator test, which were entirely from mild group. Conclusion Positive rate of bronchodilator test increases depending on the aggravation of airflow obstruction in patients with asthma. The patients with normal pulmonary function can also reveive the bronchodilator test. Specific flow volume loops are showed in positive cases of normal group. It is a lifelong process and needs individualized management in the control or treatment of asthma. Pulmonary function test examined regularly is beneficial to guide clinical treatment and manage asthma.

Key words: Pulmonary function test, Bronchodilator test, Asthma, Forced expiratory volume in one second, Forced expiratory volume in one second /forced vital capacity

CLC Number: 

  • R562.2+5
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