Journal of Shandong University (Health Sciences) ›› 2018, Vol. 56 ›› Issue (7): 81-85.doi: 10.6040/j.issn.1671-7554.0.2018.288

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Efficacy of transurethral resection of bladder tumor in the treatment of muscle-invasive bladder cancer

LIU Jie1, CUI Wei2, CHE Zi2, CUI Zhiqiang2, WANG Cezheng2, WANG Tong2, LI Ming2, LIU Ling3, YANG Quancheng2, SUN Bin2, GAO Dianjun1, Nie Qingsheng2   

  1. 1. Weifang Medical University, Weifang 261000, Shandong, China;
    2. Department of Urology, Central Hospital of Zibo, Zibo 255000, Shandong, China;
    3. Medical Records Room, Central Hospital of Zibo, Zibo 255000, Shandong, China
  • Published:2022-09-27

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Abstract: Objective To investigate the clinical efficacy and safety of transurethral resection of bladder tumor(TURBT)for T2 stage muscle invasive bladder cancer(MIBC). Methods The clinical data of 101 MIBC cases treated during Jan. 2008 and Feb. 2013 were retrospectively analyzed. All tumors were pathologically T2 stage. The patients were divided into the observation group(n=84)and control group(n=17). Patients in the observation received TURBT, during which the bladder wall around the tumor was removed thoroughly, including 1.5 cm bladder mucosa. Patients in the control group underwent radical cystectomy and pelvic lymph node dissection. The recurrence, complications, survival rate and quality of life of the two groups were recorded and compared. Results The average operation time was shorter in the observation group than in the control group［(53.1±10.3)min vs(202.4±31.5)min］. The average hospitalization time was shorter in the observation group than in the control group ［(11.7±1.7)d vs(28.0±4.7)d ］. 山 东 大 学 学 报 (医 学 版)56卷7期 -刘杰,等.经尿道膀胱肿瘤电切术治疗肌层浸润性膀胱癌的临床疗效 \=- The average intraoperative blood loss was less in the observation group than in the control group［(13.7±6.3)mL vs(470.6±143.1)mL］. The differences were statistically significant(P<0.001). The 1-year, 3-year and 5-year survival rate were 97.6%, 84.5%, and 78.5% in the observation group, and were 94.1%, 82.4% and 76.4% in the control group, with no statistical differences(P>0.05). In the observation group, urinary tract infection occurred in 4 cases, who were cured after anti-infection treatment. In the control group, hydronephrosis, ureteral obstruction and acute intestinal obstruction occurred in 1 case respectively. The complication rate and hospitalization costs were lower in the observation group than in the control group. In the observation group, the bladders were preserved, and the quality of life was significantly improved. Conclusion For patients with T2 stage, sporadic, small size(diameter ≤2 cm)MIBC, TURBT is safe and effective, and can improve patients’ quality of life. For patients with multiple, large size(diameter >2 cm)MIBC, radical cystectomy is the first choice.

Key words: Transurethral resection of bladder tumor, Radical cystectomy, Muscle-invasive bladder cancer, Survival rate

CLC Number: 

  • R737.14
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