Abstract: Objective To discuss the curative effect and security of milrinone atomization inhalation on treating severe pneumonia complicated with heart failure in noenates and infants. Methods A total of 240 cases with severe pneumonia complicated with heart failure in the fourth Peoples Hospital of Jinan City from 2012 to 2015 were randomly divided into control group and observation group, 120 in each group. The control group was treated with digitalis, diuretic, and other conventional therapies; on this basis, the observation group was treated additionally with milrinone atomization inhalation. Changes of the clinical efficacy and cardiac function indexes of the two groups were observed. Results After 5 days of treatment, clinical symptoms, signs and cardiac function indexes were improved significantly in the two groups. The improvement of cardiac function indexes in the observation group was better than that in the control group. The difference of clinical efficacy and cardiac function indexes before and after the treatment in the two groups were statistically significant(P<0.05). Conclusion On the basis of routine treatment such as digitalis and diuretic therapy, milrinone atomization inhalation can reduce the pulmonary circulation resistance, cardiac preload and afterload, thus effectively improve the heart function in noenates and infants with severe pneumonia complicated with heart failure.

Key words: Severe pneumonia, Pulmonary artery hypertension, Milrinone atomization, Heart failure