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山东大学学报(医学版)

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18F-FDG PET-CT评价非小细胞肺癌淋巴结分期的价值

张成琪1,王广丽2,宋吉清2,姚树展2,刘庆伟2,陈静2   

  1. 1. 山东省千佛山医院放射科, 山东 济南 250014;2. 山东省立医院放射科, 山东 济南 250021
  • 收稿日期:2007-04-09 修回日期:1900-01-01 出版日期:2007-10-24 发布日期:2007-10-24
  • 通讯作者: 张成琪

18F-FDG PET-CT for lymph node staging in non-small cell lung cancer

ZHANG Cheng-qi1,WANG Guang-li2,SONG Ji-qing2,YAO Shu-zhan2,LIU Qing-wei2,CHE Jing2   

  1. 1. Department of Radiology, Shandong Qianfoshan Hospital;2. Department of Radiology, Shandong Provincial Hospital, Jinan 250021, Shandong, China
  • Received:2007-04-09 Revised:1900-01-01 Online:2007-10-24 Published:2007-10-24
  • Contact: ZHANG Cheng-qi

摘要: 目的:探讨18F-FDG PET-CT显像对非小细胞肺癌淋巴结分期的应用价值。方法:对在山东省立医院放射科行18F-FDG PET-CT检查,经病理证实为非小细胞肺癌且无远处转移的79例患者进行研究,并与同期CT对照,比较二者对纵隔淋巴结分期的价值。以病理结果为“金标准”对PET-CT和CT的结果进行统计学分析评价。结果:79例患者中共有268枚淋巴结转移。对淋巴结转移的诊断敏感性、特异性、准确性,PET-CT分别为:82.84%、96.70%、89.83%;CT分别为58.58%、72.89%、65.80%。前者明显优于后者。与病理符合的肺癌N分期,PET-CT 73例,CT 58例,PET-CT的诊断准确性明显高于CT(χ2=10.05, P<0.01)。结论:18F-FDG PET-CT对于非小细胞肺癌的淋巴结分期具有重要的应用价值,是一种有效的无创性影像学检查方法。

关键词: X线计算机, 诊断, 发射型计算机, 体层摄影术, 体层摄影术, 肿瘤分期 , 肺肿瘤

Abstract: Objective: To investigate the clinical value of 18F-FDG PET-CT for non-small cell lung cancer in lymph node staging. Methods:18F-FDG PET-CT (Discovery LS PET-CT in Department of Radiology of Shandong Provincial Hospital) images of 79 patients who had undergone surgeries for histopathologically proved non-small cell lung cancers without distant metastases were analyzed. PET-CT results were compared with the CT data. Findings of both modalities were compared with pathological results and were statistically analyzed. Results: There were 268 lymph node metastases in 79 patients. The sensibility, specificity and accuracy of PET-CT and CT for detecting lymphoid node metastasis were 82.84%, 96.70% and 89.83% and 58.58%, 72.89% and 65.80%, respectively. The former was obviously better than the latter. Overall tumor stage was correctly classified as N stage with CT in 58 patients and with PET-CT in 73 patients. Differences in the accuracy of lymphoid node staging between PET-CT and CT were significant (χ2=10.05, P<0.01). Conclusion: PET-CT is a very effective imaging modality for lymph node staging of nonsmall cell lung cancer.

Key words: Lung neoplasms, Tomography, emission-computed, Tomography, X-ray computed, Diagnosis, Neoplasm staging

中图分类号: 

  • R817.4
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