山东大学学报（医学版） ›› 2015, Vol. 53 ›› Issue (7): 34-38.doi: 10.6040/j.issn.1671-7554.0.2014.933
代高赛, 马婷婷, 江立玉, 霍强, 孔晓丽, 景楚瑜, 杨其峰
DAI Gaosai, MA Tingting, JIANG Liyu, HUO Qiang, KONG Xiaoli, JING Chuyu, YANG Qifeng
摘要： 目的 探讨术中冰冻病理对乳腺导管内乳头状肿瘤(IDPN)的诊断价值及相关影响因素。方法 对2007年1月至2013年12月收治的560例术后石蜡病理确诊为乳腺IDPN的患者进行回顾性分析, 对比术中冰冻病理与术后石蜡病理结果, 观察术中冰冻病理诊断准确率及其相关影响因素。结果 ① 术中冰冻病理对于IDPN总体诊断准确率为85.1%,其中导管内乳头状瘤与导管内乳头状癌诊断准确率分别为88.9%、49.0%, 差异有统计学意义(P<0.05);② 16例(3.1%)患者诊断病理级别升高, 1例(0.2%)患者诊断病理级别降低;③ 伴有及不伴有乳头溢液患者诊断准确率分别为89.2%、79.4%, 差异有统计学意义(P<0.05)。结论 术中冰冻病理对于诊断IDPN意义重大, 导管内乳头状瘤诊断准确率高于导管内乳头状癌, 伴有乳头溢液患者比不伴有者术中冰冻病理诊断准确率高。
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