FibroScan检测肝脏硬度影响因素的多元回归分析

山东大学学报(医学版) ›› 2013, Vol. 51 ›› Issue (8): 69-73.

FibroScan检测肝脏硬度影响因素的多元回归分析

王爱光1，崔蕾2，王桂玲2，李建志2，张梅芳2，赵敏2，孙爱华2，单容2

1. 山东大学附属千佛山医院肿瘤科，济南 250014；2济南市传染病医院特检科，济南 250021

收稿日期:2012-11-20 出版日期:2013-08-10 发布日期:2013-08-10
通讯作者: 单容, Email:shanrong@126.com

Multiple regression analysis of influencing factors in FibroScan detecting liver stiffness

WANG Ai-guang1， CUI Lei2, WANG Gui-ling2, LI Jian-zhi2, ZHANG Mei-fang2， ZHAO Min2， SUN Ai-hua2， SHAN Rong2

1. Department of Oncology, Qianfoshan Hospital Affiliated to Shandong University, Jinan 250014, China；
2. Department of Function, Jinan Infectious Disease Hospital, Jinan 250021, China

Received:2012-11-20 Online:2013-08-10 Published:2013-08-10

摘要/Abstract

摘要：

目的运用多元回归分析的方法，寻找影响FibroScan测定肝纤维化的独立预测因子。方法选取住院及门诊需行肝穿刺活组织检查确诊的患者181例，于肝活检手术当天进行FibroScan检测肝脏硬度值（LSM），同时收集患者临床信息及±3d的常规血液检测指标。将筛选出的10个自变量进行多元回归分析。结果多元回归分析结果显示，血小板（PLT）、血清白蛋白（ALB）、凝血酶原活动度（PTA）、体质量指数（BMI）为独立预测因子。结论在FibroScan检测肝脏硬度时，PLT、ALB、PTA和BMI值可能会对检测结果产生影响。

关键词: FibroScan；肝脏硬度；独立预测因子；多元回归分析

Abstract:

Objective To determine the independent predictors influencing liver stiffness detection with FibroScan by multiple regression analysis. Methods One hundred and eighty-one inpatients and outpatients who required liver biopsy were enrolled. Liver stiffness measurement (LSM) was detected by FibroScan on the day of performing liver biopsy, and clinical information and routine biochemical tests data (±3 days) were gathered. Ten factors were chosen for the multiple regression analysis. Results Multiple regression analysis showed that platelet(PLT), serum albumin(ALB), prothrombin activity(PTA) and body mass index(BMI) were independent predictors. ConclusionIn FibroScan detection, PLT, ALB, PTA and BMI might be influencing factors.

Key words: FibroScan; Liver stiffness; Independent predictor; Multiple regression analysis

中图分类号:

R575.2

王爱光1，崔蕾2，王桂玲2，李建志2，张梅芳2，赵敏2，孙爱华2，单容2. FibroScan检测肝脏硬度影响因素的多元回归分析[J]. 山东大学学报(医学版), 2013, 51(8): 69-73.

WANG Ai-guang1， CUI Lei2, WANG Gui-ling2, LI Jian-zhi2, ZHANG Mei-fang2， ZHAO Min2， SUN Ai-hua2， SHAN Rong2. Multiple regression analysis of influencing factors in FibroScan detecting liver stiffness[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2013, 51(8): 69-73.

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