踝臂指数对心血管高危患者全因及心血管死亡率的预测作用

山东大学学报(医学版) ›› 2013, Vol. 51 ›› Issue (1): 53-.

踝臂指数对心血管高危患者全因及心血管死亡率的预测作用

唐海荣,袁斌斌,胡大一,布艾加尔·哈斯木

南京医科大学附属南京明基医院心内科, 南京 210019

收稿日期:2012-05-07 出版日期:2013-01-10 发布日期:2013-01-10
通讯作者: 布艾加尔·哈斯木(1969- )，女，副主任医师，主要从事心血管疾病研究。 E-mail:buaijiaer@163.com
作者简介:唐海荣(1976- )，女，主治医师，主要从事心血管疾病研究。 E-mail: thr129@chinaren.com

Prediction of ankle-brachial index to all-cause and cardiovascular mortalities in patients with high cardiovascular risk

TANG Hai-rong, YUAN Bin-bin, HU Da-yi, Buaijiaer·Hasimu

Department of Cardiology, Nanjing BenQ Hospital Affiliated to Nanjing Medical University, Nanjing 210019, China

Received:2012-05-07 Online:2013-01-10 Published:2013-01-10

摘要/Abstract

摘要：

目的评估心血管高危患者踝臂指数(ABI)与1年全因及心血管死亡率的相关性。方法选择3179例心血管高危患者，检测静息状态下ABI，以ABI＜0.9为低ABI。将患者分为4组：冠状动脉粥样硬化性心脏病(CHD)组、缺血性脑卒中(IS)组、糖尿病(DM)组、极高危(VHR)组。随访1～1.5年，评价ABI与1年全因及心血管死亡率的相关性。结果低ABI发生率为28.2%。低ABI者的全因死亡率及心血管死亡率(14.2%，6.6%)高于ABI正常者(6.5%，2.5%)(P＜0.01)。各组低ABI者全因死亡率及心血管死亡率均高于ABI正常者(P＜0.01)。DM患者全因死亡及心血管死亡风险均高于其余3组。结论 ABI是死亡率强有力的独立预测因子，其中低ABI患者的1年全因死亡及心血管死亡风险大幅度增加。

关键词: 踝臂指数; 高危人群；心血管疾病; 死亡率

Abstract:

Objective To assess the correlation between ankle-brachial index (ABI) and 1-year all-cause and cardiovascular mortalities in patients with high cardiovascular risk. Methods 3179 patients with high cardiovascular risk were selected. The ABI indexes at resting state were detected, and ABI<0.9 was regarded as low ABI. The patients were divided into four groups: coronary atherosclerotic heart disease (CHD) group, ischemic stroke (IS) group, diabetes mellitus (DM) group and very high risk (VHR) group. Then the patients were followed up for 1 to 1.5 years, and the correlations between ABI and 1-year all-cause and cardiovascular mortalities were assessed. Results The incidence of low ABI was 28.2%. The all-cause and cardiovascular mortalities (14.2%, 6.6%) in patients with low ABI were obviously higher than those in patients with normal ABI (6.5%, 2.5%) (P<0.01). In each group, the all-cause and cardiovascular mortalities in patients with low ABI were obviously higher than those in patients with normal ABI(P<0.01). The all-cause and cardiovascular mortality risks in DM group were higher than those in the other three groups. Conclusion ABI is an independent predictor of mortality, and patients with low ABI have a substantial increase in the risk of all-cause and cardiovascular death.

Key words: Ankle-brachial index; High-risk group； Cardiovascular diseases; Mortality rate

中图分类号:

R541

唐海荣,袁斌斌,胡大一,布艾加尔·哈斯木. 踝臂指数对心血管高危患者全因及心血管死亡率的预测作用[J]. 山东大学学报(医学版), 2013, 51(1): 53-.

TANG Hai-rong, YUAN Bin-bin, HU Da-yi, Buaijiaer·Hasimu. Prediction of ankle-brachial index to all-cause and cardiovascular mortalities in patients with high cardiovascular risk[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2013, 51(1): 53-.

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